Metabolic effects of insulin

Created by Mo

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What is the effect of insulin on phosphofructokinase and its overall impact on glucose metabolism?

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Insulin stimulates phosphofructokinase, which favours glycolysis, leading to increased glucose utilization.

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Insulin's role in glycolysis

What is the effect of insulin on phosphofructokinase and its overall impact on glucose metabolism?

Insulin stimulates phosphofructokinase, which favours glycolysis, leading to increased glucose utilization.

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Insulin's effect on gluconeogenesis

How does insulin affect PEPCK and what is the clinical significance of this action?

Insulin inhibits PEPCK, which depresses gluconeogenesis, contributing to hypoglycemia.

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Insulin's influence on glycogen metabolism

What is the action of insulin on glycogen synthase and its overall effect on glycogen metabolism?

Insulin activates glycogen synthase, promoting glycogen deposition, which helps lower blood glucose levels.

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Insulin's impact on lipid metabolism

What is the effect of insulin on hormone-sensitive lipase and its implications for lipid metabolism?

Insulin inhibits hormone-sensitive lipase, which reduces lipolysis and decreases ketogenesis, promoting fat storage.

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Insulin's effect on protein metabolism

How does insulin influence protein metabolism through transaminase?

Insulin inhibits transaminase, which reduces catabolism and favours general anabolism, enhancing protein synthesis.

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