What disease is caused by Trichomonas vaginalis?
Trichomoniasis.
What is the habitat of Trypanosoma brucei?
Blood and tissue.
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Trichomoniasis

What disease is caused by Trichomonas vaginalis?

Trichomoniasis.

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Trypanosoma sp.

What is the habitat of Trypanosoma brucei?

Blood and tissue.

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Giardia lamblia

What are the synonyms for Giardia lamblia?

Giardia duodenalis, Giardia intestinalis, Munsaka.

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Trichomonas vaginalis

What is the geographical distribution of Trichomonas vaginalis?

Worldwide, affecting all social groups.

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Leishmania spp.

Where is the habitat of Leishmania spp.?

Blood and tissue.

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Flagellates

What are flagellates?

Organisms with one or more whip-like appendages called flagella.

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Giardia lamblia

What is the life cycle of Giardia lamblia?

The life cycle involves two stages: a cyst stage and a trophozoite stage. Infection occurs when a person ingests the cyst form of the parasite.

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Clinical Features

What are the clinical features of Giardiasis?

Abdominal pain, bloating, flatulence, anorexia, nausea, and weight loss.

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Parasite Habitat

Where does Trichomonas vaginalis primarily affect?

The urogenital tract.

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Lab Diagnosis

What is examined in stool microscopy?

Presence of cysts and trophozoites.

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Pathogenesis

How do trophozoites of Giardia lamblia cause damage to the intestinal epithelium?

They adhere to enterocytes using their adhesive disk, disrupting the mucosal barrier, causing villus blunting (atrophy), nutrient loss, diarrhea, and malnutrition.

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Giardiasis

What disease is caused by Giardia lamblia?

Diarrhoea, also known as Giardiasis, lambliasis, or 'Traveller’s disease'.

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Mode of Transmission

What are the modes of transmission for Trichomonas vaginalis?

Sexually and vertically (rare).

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Trichomoniasis

How is chronic trichomoniasis infection linked to an increased risk of cervical cancer?

It is linked to inflammatory response and alterations in the cervical epithelium.

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Prevention of giardiasis

What is the recommended method for the prevention of giardiasis?

Proper disposal of waste and fecal matter, practice of personal hygiene, prevention of food contamination, boiling and filtration of water.

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Trichomonas vaginalis

Where does Trichomonas vaginalis reside?

In the vagina and urethra.

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Trichomoniasis

What complications can untreated trichomoniasis lead to in women?

Susceptibility to other STIs, including HIV, and an increased risk of cervical cancer.

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Clinical Features

How are Giardia stools described?

Loose, bulky, frothy, and/or greasy with the absence of blood or mucus.

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Prevention of Giardiasis

What are the measures for preventing Giardiasis?

Good personal hygiene, proper disposal of faeces, water purification, and treating Giardiasis patients properly.

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Clinical Features

What are the clinical presentations of Trichomonas vaginalis in females?

Vaginal discharge (often frothy yellow-green & malodorous), vaginitis, cervicitis, vaginal itching, dyspareunia, and asymptomatic carriers.

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Trichomonas vaginalis

What does Balanitis refer to?

Inflammation of the glans or the head of the penis.

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Trichomoniasis

What problems can PID cause?

Chronic pelvic pain, infertility, and ectopic pregnancy.

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Lab Diagnosis

What do serology tests detect in the lab diagnosis of T. vaginalis?

Antibodies & antigens.

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Giardiasis

What are the potential consequences of Giardiasis?

Malabsorption and steatorrhea (excessive loss of fat in the feces).

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Giardia lamblia

What is the habitat of Giardia lamblia?

Lumen of the small intestine.

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Trichomonas vaginalis

What are the clinical presentations of Trichomonas vaginalis in males?

Urethritis, Epididymitis, Prostatitis, Discharge, Burning after ejaculation or urination.

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Lab Diagnosis

What are the specimens used for lab diagnosis in males?

Urethral swab and urine.

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Trichomonas vaginalis

How long can Trichomonas vaginalis survive outside the body?

15 - 48 hours.

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Trichomonas vaginalis

Does Trichomonas vaginalis have a cyst stage?

No, it does not have a cyst stage.

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Trichomonas vaginalis

How many species does the genus Trichomonas have that occur in humans?

3 species.

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Trichomonas vaginalis

What is the pathogenic species of Trichomonas occurring in humans?

T. vaginalis.

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Trichomoniasis

What discomfort can sexual intercourse cause in untreated trichomoniasis?

Pain and discomfort.

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Lab Diagnosis

What are the specimens used for lab diagnosis of giardiasis?

Stool sample, duodenal contents by aspiration, upper small intestinal biopsies.

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Mode of Transmission

What is the mode of transmission for the parasite?

Fecal-oral: ingestion of cysts in contaminated water & food, oral-anal sex, and animal reservoir.

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Parasite Habitat

Where does Giardia lamblia primarily inhabit?

Small intestine, including the duodenum and upper jejunum.

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Giardia lamblia

Where is Giardia lamblia prevalent?

In tropical and developing countries, as well as areas with low sanitation.

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Trichomonas vaginalis

What is associated with a higher prevalence of Trichomonas vaginalis?

Having multiple sexual partners.

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Trichomoniasis

What are the complications of untreated trichomoniasis in men?

Prostatitis, epididymitis, urethritis, pain during sexual intercourse, and infertility issues.

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Parasite Habitat

Where does Trichomonas vaginalis mainly reside in males?

In the urethra and prostate.

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Clinical Features

What is the characteristic of the vaginal discharge in Trichomonas vaginalis infection?

Frothy yellow-green and malodorous.

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Lab Diagnosis

What type of culture medium supports the growth of T. vaginalis in culture diagnosis?

Special culture medium.

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Trichomonas vaginalis

Where does T. tenax, a non-pathogenic species of Trichomonas, occur in the human body?

In the mouth/buccal cavity.

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Flagellates

What is the function of flagellum in flagellates?

It is for motility.

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Flagellates

What are the three main categories of flagellates?

Intestinal flagellates, Urogenital flagellates, Haemoflagellates.

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Trichomonas vaginalis

What is the infective form and replication stage of Trichomonas vaginalis?

Trophozoite stage.

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Giardia lamblia

What is the geographical distribution of Giardia lamblia?

It is cosmopolitan, prevalent in the tropics and subtropics.

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Parasite Habitat

Where does Trichomonas vaginalis mainly reside in females?

In the vagina and urethra.

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Trichomonas vaginalis

What happens when T. vaginalis invades epithelial cells?

It causes inflammation and micro abrasions/micro-ulceration.

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Giardia lamblia

Which stage of Giardia lamblia is pathogenic and considered the diagnostic form?

Trophozoite (or vegetative form)

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Giardia lamblia

How many stages does Giardia lamblia have?

Two stages: trophozoite and cyst.

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Pathogenesis

What is the range of the incubation period for the pathogenesis of the condition?

1 – 2 weeks, with reported cases of 1 – 75 days.

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Lab Diagnosis

What specimens are used for lab diagnosis of Munsaka in females?

High vaginal swab (HVS) and urine.

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Trichomoniasis

What are the common medications used to treat Trichomoniasis?

Metronidazole (Flagyl) and Tinidazole (Tindamax).

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Giardiasis

What is the drug of choice for the treatment of giardiasis?

Metronidazole (Flagyl®).

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Trichomonas vaginalis

How does T. vaginalis interact with the urogenital tract?

It adheres to the epithelial cells lining the urogenital tract.

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Trichomonas vaginalis

What does Balanoposthitis refer to?

Inflammation of the foreskin and glans.

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Trichomoniasis

What is PID?

PID stands for Pelvic Inflammatory Disease, which is an infection of the female reproductive organs.

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Trichomonas vaginalis

Where does T. hominis, a non-pathogenic species of Trichomonas, occur in the human body?

In the intestine.

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Trichomonas vaginalis

What are the complications of Trichomonas vaginalis infection in males?

Balanoposthitis and Balanitis.

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Giardiasis

Which drug for giardiasis treatment is available in liquid formulation?

Furazolidone (Furoxone®).

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Lab Diagnosis

What is the purpose of microscopy in the lab diagnosis of T. vaginalis?

To detect a trophozoite.

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Mode of Transmission

How do asymptomatic carriers of Trichomonas vaginalis contribute to transmission?

They facilitate transmission to sexual partners.

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Giardiasis

Which drug is recommended for the treatment of giardiasis during pregnancy?

Paramomycin (Humatin®).

p.39
Trichomoniasis

What complications can untreated trichomoniasis lead to in women?

Damage to the reproductive organs, including Pelvic Inflammatory Disease (PID), chronic pelvic pain, infertility, and ectopic pregnancy.

p.9
Giardia lamblia

What are the two stages in which Giardia lamblia exists?

1. Trophozoite (or vegetative form) 2. Cyst (or cystic form)

p.36
Lab Diagnosis

What is the purpose of Polymerase Chain Reaction (PCR) in the lab diagnosis of T. vaginalis?

To detect the DNA or RNA of T. vaginalis.

p.43
Prevention of Giardiasis

What method of water treatment cannot kill Giardia cysts?

Chlorination of water.

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Prevention of Giardiasis

What method of water treatment can kill Giardia cysts?

Iodination of water.

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Clinical Features

What symptom may females with Trichomonas vaginalis infection experience during sexual intercourse?

Dyspareunia (pain during sexual intercourse).

p.9
Giardia lamblia

Which stage of Giardia lamblia is the infective stage and also considered the diagnostic form?

Cyst (or cystic form)

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