What is fibrinoid necrosis in the context of rheumatic fever?
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Fibrinoid necrosis refers to the necrosis of myocardial tissue due to deposition of fibrin and inflammatory cells, a characteristic feature of rheumatic fever.
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What is fibrinoid necrosis in the context of rheumatic fever?
Fibrinoid necrosis refers to the necrosis of myocardial tissue due to deposition of fibrin and inflammatory cells, a characteristic feature of rheumatic fever.
What are the diagnostic criteria for Acute Rheumatic Fever?
2 Major criteria or 1 major and 2 minor criteria
Who authored the article 'Carapetis et al Lancet 2006'?
Carapetis et al
Who authored the study on Rheumatic Fever and Rheumatic Heart Disease in children?
John Lawrenson
What is the significance of a chest radiograph on admission?
It helps in assessing the extent of cardiac involvement in patients with rheumatic fever.
Which universities were involved in the study of Rheumatic Fever and Rheumatic Heart Disease in children?
Universities of Stellenbosch and Cape Town
What imaging technique is discussed in the article?
Echo
What are the Duckett Jones criteria used for?
Making the clinical diagnosis of acute rheumatic fever
What is the most common cause of acquired heart disease in children in developing countries?
Rheumatic fever
What valve is usually involved in Acute Rheumatic Fever?
Mitral valve
Which valve can be involved together with the mitral valve in Acute Rheumatic Fever?
Aortic valve
What is the significance of the Bland, Jones Circulation 1951?
The Bland, Jones Circulation 1951 was a landmark study that provided important insights into the pathophysiology of rheumatic fever and rheumatic heart disease.
What does RHD stand for?
Rheumatic Heart Disease
What is the focus of the book 'Perspectives on the Mitral Valve' by Barlow?
The focus of the book is on the mitral valve.
What are Anitschkow cells?
Anitschkow cells are enlarged macrophages with a 'caterpillar' or 'owl-eye' appearance found in the myocardium in rheumatic fever.
Who authored the article 'Carapetis et al Lancet 2006'?
Carapetis et al
What does ARF stand for?
Acute Rheumatic Fever
What are the outcomes of rheumatic fever in Uganda from 2017 to 2021?
The outcomes of rheumatic fever in Uganda from 2017 to 2021 were documented in a study by Wirth et al. published in The Lancet Global Health in 2024.
What term is used to describe the presence of RHD without any noticeable symptoms?
Subclinical RHD
At what age do most deaths occur within 2 years after enrolment?
12 years old
Where have all the patients with acute rheumatic fever gone?
The incidence of acute rheumatic fever has decreased in developed countries.
What is the estimated incidence of rheumatic heart disease (de novo hospital presentations) according to Sliwa et al.?
The estimated incidence of rheumatic heart disease (de novo hospital presentations) is 719-727 per 100,000 population.
What are the symptoms presented by the 40-year-old man with moderate mitral regurgitation?
Shortness of breath with effort, palpitations, inability to move left arm and left leg
What is the abbreviation for the journal 'Current Treatment Options in Cardiovascular Medicine'?
Curr Treat Options Cardio Med
What is the estimated number of strokes caused by Rheumatic heart disease?
300,000 strokes
What is the St Jude Mitral valve prosthesis?
It is a mechanical heart valve used to replace a diseased or damaged mitral valve.
What percentage of cerebrovascular accidents (CVA’s) are attributed to Rheumatic heart disease?
3 - 7.5%
What is a common consequence of Rheumatic heart disease?
Chronic valvular heart disease
What is the leading cause of acquired heart disease in children in developing countries?
Rheumatic Fever
What does ARF stand for?
Acute Rheumatic Fever
What term is used to describe the presence of RHD without any noticeable symptoms?
Subclinical RHD
What is the most common cause of myocarditis in children in the Western Cape?
TB
How can we prevent people at risk from getting rheumatic fever?
By treating streptococcal throat infections with antibiotics to prevent the development of rheumatic fever.
What is the relationship between Rheumatic Fever and Rheumatic Heart Disease?
Rheumatic Fever can lead to Rheumatic Heart Disease in children.
What are some of the characteristics, complications, and gaps in evidence-based interventions in rheumatic heart disease documented in the REMEDY study?
The Global Rheumatic Heart Disease Registry (the REMEDY study) documented characteristics, complications, and gaps in evidence-based interventions in rheumatic heart disease.
What is the leading cause of acquired heart disease in children in the Western Cape?
Kawasaki Disease
Who is at risk of developing rheumatic heart disease?
Rheumatic heart disease primarily affects children and young adults who have had untreated strep throat or scarlet fever caused by group A streptococcal infection.
What is the most common complication of Rheumatic Fever?
Rheumatic Heart Disease
Who are the authors of the article?
Nina C. Wunderlich, Roy Beigel, Robert J. Siegel
What does RHD stand for?
Rheumatic Heart Disease
What is the title of the article in The Lancet Global Health from 2014?
Active surveillance for rheumatic heart disease in endemic regions: a systematic review and meta-analysis of prevalence among children and adolescents
What are the findings in a 25-year-old woman in her 2nd month of pregnancy who is short of breath with effort over the last week?
S1 loud, P2 loud, 2/4 mid-diastolic murmur at apex, fine crackles on inspiration at lung bases
What is the Global Rheumatic Heart Disease Registry also known as?
The REMEDY study
What is a common cause of endocarditis in children?
Acute rheumatic fever
What is a common acquired cardiac disease in children that can lead to chronic valvular heart disease?
Acute rheumatic fever
What term is used to describe the situation where ARF is not diagnosed or treated properly, leading to the development of RHD?
Unrecognized ARF leading to Recurrence of RHD
What are you thanking for?
Listening
What is a common cause of pericarditis in children?
TB
What is the long-term consequence of rheumatic fever affecting the heart?
Rheumatic heart disease
What is the title of the article?
JACC: Cardiovascular Imaging, Volume 6, Issue 11, 2013, 1191 - 1205
In which volume and issue was the article published?
Volume 2 Issue 12
What term is used to describe the situation where ARF is not diagnosed or treated properly, leading to the development of RHD?
Unrecognized ARF
What was the prevalence of rheumatic heart disease among children and adolescents according to the systematic review and meta-analysis?
At least 10 times more common
