What is the primary take-home message regarding vitamin D3 supplementation?
Click to see answer
Unless you get enough sun exposure to maintain a tan, you should supplement vitamin D3 for the wide range of potential benefits, even if they’re small.
Click to see question
What is the primary take-home message regarding vitamin D3 supplementation?
Unless you get enough sun exposure to maintain a tan, you should supplement vitamin D3 for the wide range of potential benefits, even if they’re small.
What is the primary role of Vitamin E in the body?
Vitamin E acts as an antioxidant and plays important roles in cell membranes and cell signaling.
Which type of diet is at significant risk of suboptimal potassium intake?
Diets rich in grains and low in vegetables.
What is considered normal systolic blood pressure according to most official guidelines?
Normal systolic blood pressure is below 120 or 130 mm Hg.
What types of foods are recommended to ensure adequate Vitamin K intake?
Fermented foods, starchy vegetables, and whole foods.
How can you diagnose vitamin B12 deficiency?
With bloodwork.
What should you do if your blood pressure is not in the normal range?
Consider sodium restriction or blood pressure medication.
Why is Vitamin D important for strength trainees?
It is necessary for optimal bone strength, mineral metabolism, immune function, neuromuscular functioning, and testosterone synthesis.
Why should pregnant women supplement with folate?
Pregnant women should supplement with 200+ mcg of folate to meet increased nutritional needs during pregnancy.
What is the richest source of dietary vitamin K1 (phylloquinone)?
Green leafy vegetables.
What can be a consequence of over-supplementation of vitamins and minerals?
It can cause deficiencies in other micronutrients due to interactions between vitamins and minerals.
Which micronutrients are often lacking in most multivitamins?
Vitamins D and K, calcium, magnesium, iron, and iodine.
Why might the correlation between sodium intake and health risks be questioned?
Because it might be the overall diet, not just sodium intake, that increases the risk of heart-related incidents.
What are carotenoids often referred to as?
Provitamin A.
What are the specific risks for individuals who consume less than 2.3 g of sodium per day?
They had a 37% higher CVD mortality and 28% higher all-cause mortality than those who consumed more sodium.
What are some of the key functions of calcium in the body?
Neuromuscular functioning, satiety signaling, regulation of blood flow, and bone health.
How does calcium intake affect athletes in terms of fat gain?
Athletes that consume more calcium tend to gain less fat than those who consume little calcium, independent of energy intake.
Which cells in the human body are affected by Vitamin B12?
Every cell of the human body.
How is chloride most commonly consumed?
Chloride is almost exclusively consumed along with sodium in table salt (sodium chloride with 60% chloride).
Why is potassium supplementation above 100 mg per day generally inadvisable?
Because it can cause digestive problems and, in large amounts, can be lethal due to rapid absorption.
What is the Recommended Dietary Allowance (RDA) of vitamin C for adult men?
90 mg
What serum 25-hydroxyvitamin D level is now considered the minimum target by many organizations?
50 nmol/l.
What effect does supplementing a gram or more of vitamin C have on muscle growth?
It interferes with anabolic muscle signaling, strength development, and muscle growth.
How does Vitamin C help prevent inflammation?
Vitamin C prevents free radical damage and oxidative stress, thereby keeping inflammation in check.
How does Vitamin K interact with other nutrients during bone formation?
Vitamin K interacts with vitamin D and calcium during bone formation.
Why is vitamin K deficiency difficult to diagnose?
Bloodwork can only show vitamin K levels in serum, not in the intestines.
How do doctors commonly test for vitamin K deficiency?
By seeing how long it takes for your blood to clot.
Why is sodium essential for humans?
It helps maintain fluid balance in various tissues as a key electrolyte.
Which foods are rich in vitamin E?
Plant foods, especially the oils in nuts and green vegetables.
What is the Latin phrase that emphasizes the connection between physical health, mental health, and optimal performance?
Mens sana in corpore sano (A healthy mind in a healthy body).
What should you do for best results in assessing your health and nutrient needs?
Have bloodwork done.
What is the primary function of chloride in the body?
Chloride functions as an electrolyte.
What can over-supplementation of one Vitamin E isoform cause?
It can cause competitive uptake inhibition of the other isoforms, potentially leading to a deficiency and imbalance in the body.
Why should vegetarians supplement with a B-vitamin complex?
Vegetarians should supplement with a B-vitamin complex, including 4+ mcg of Vitamin B12, because their diet may lack sufficient B-vitamins.
Is there a need for a multivitamin if your diet is already good?
No, there is no need for a multivitamin if your diet is already good.
Why does the body need to consume vitamin K regularly despite it being a fat-soluble vitamin?
The body does not retain vitamin K very effectively.
How much vitamin E is recommended during lactation?
19 mg (28.4 IU) of RRR α-tocopherol.
How does the absorption of vitamin E improve?
Vitamin E’s absorption is much higher in a fatty meal.
What are some functions of potassium in the body?
Potassium is needed for nerve transmission, muscular contractions, blood pressure regulation, kidney functioning, calcium absorption, insulin secretion, and maintaining acid-base balance.
What processes in the human body are especially affected by Vitamin B12?
DNA synthesis and regulation, fatty acid metabolism, and amino acid metabolism.
What is the recommended sodium intake for strength trainees on training days?
5 - 7 grams per day.
What is the primary take-home message for adequate potassium intake?
Consuming a lot of whole foods, regardless of the specific types.
What colors are plants high in carotenoids typically?
Orange and red.
What type of vitamin is Vitamin C?
Vitamin C is a water-soluble antioxidant.
Where is vitamin K2 (menaquinone) found in large amounts?
In fermented foods like aged cheese.
What health issues are associated with high sodium intake?
Increased blood pressure, cardiovascular disease (CVD), and stroke.
What type of research primarily supports the health effects of sodium intake?
Cross-sectional, observational research from epidemiology.
What is Vitamin A also called?
Preformed vitamin A or retinoid.
What is the RDA for vitamin E for adults?
15 mg (22.4 IU) of RRR α-tocopherol.
Which foods are sources of Vitamin K2?
Vitamin K2 is produced by bacteria in foods such as cheese and natto.
How much potassium does the average adult need per day?
The Adequate Intake of potassium is 4.7 grams per day for adults.
What is the advised minimum daily supplementation of vitamin D3 for nearly all untanned individuals?
At least 1000 IU/d.
What is a common misconception about Vitamin E in multivitamins?
Many people think Vitamin E is just alpha-tocopherol, but it actually has 8 different isoforms.
What is the primary take-home message regarding chloride intake?
As long as your sodium intake is under control, your chloride intake will be as well.
What is the primary take-home message regarding a high protein diet and B-vitamin requirements?
A high protein diet from whole foods generally meets B-vitamin requirements, except for vegetarians and pregnant women.
Up to what serum 25-hydroxyvitamin D level do some researchers recommend aiming for health benefits?
100 nmol/l.
What is considered normal diastolic blood pressure according to most official guidelines?
Normal diastolic blood pressure is below 80 or 85 mm Hg.
Which food has the highest β-carotene content per ½ cup cooked serving?
Spinach with 5,660 IU (472 μg).
What is the daily Adequate Intake for Vitamin K for men and women?
120 mcg for men and 90 mcg for women.
What is a popular carotenoid that can convert to retinol?
β-carotene.
What impact can micronutrients have on strength training?
They can impact the sensation of fatigue during strength training.
What is the difference between systolic and diastolic blood pressure?
Systolic blood pressure is the top pressure when the heart contracts and pumps blood, while diastolic blood pressure is the pressure when the heart relaxes and fills with blood between beats.
How can you generally achieve an optimal serum vitamin D concentration?
With 10-30 minutes of daily near-full-body sun exposure with a UV index of at least 3.
Do B-vitamins have any known toxicity mechanism at high intakes?
No, B-vitamins have no known toxicity mechanism even at very high intakes and are easily excreted in the urine.
Where is most of the body's potassium stored?
Almost all of the body's potassium is stored within cells.
What is the primary take-home message regarding vitamin E intake?
As long as your diet has enough fats and green veggies, or lots of plants in general, you shouldn’t have to worry about vitamin E. Supplementation is more likely to be harmful than helpful.
What is the recommended daily intake of folate for pregnant women?
600 mcg per day.
What might be a better daily intake of vitamin B12 for optimal health?
4 μg/day.
What are the common forms of Vitamin B12 in supplements?
Cyanocobalamin and methylcobalamin.
What is the recommended sodium intake for strength trainees on rest days?
3 - 5 grams per day.
What is the primary take-home message regarding sodium intake for healthy, exercising individuals?
Enjoy your salt to taste but keep an eye on your blood pressure periodically.
What is the recommended daily intake of vitamin C for strength trainees?
120 - 200 mg per day
What effect does a high intake of carotenoids have on your skin?
It gives your skin a yellow tint.
Which form of vitamin K intake is strongly inversely related to all-cause mortality according to epidemiological research?
Vitamin K2.
What is the chemical term for table salt?
Sodium chloride (NaCl).
What is a general rule of thumb for consuming multivitamins?
Don't consume a multivitamin that has much more than 100% of the recommended daily intake of nutrients unless you have a good reason.
What type of diet should result in adequate Vitamin A activity without the need for supplementation?
A high protein, fibrous, whole foods-based diet.
What is the role of potassium in the body?
Potassium functions as an electrolyte essential for survival, regulating fluid volumes, nerve transmission, muscular contractions, blood pressure, and kidney functioning.
Which individuals are more likely to benefit from sodium restriction?
Individuals with high blood pressure, heart failure, or chronic kidney disease.
Why are vegetables like spinach, rhubarb, and Swiss chard considered poor sources of calcium?
Because they contain large amounts of oxalic acid, which binds calcium and inhibits its absorption.
What is the role of Vitamin B9 (folic acid, folate)?
Vitamin B9 is a precursor needed to make, repair, and methylate DNA; it is a cofactor in various reactions and is especially important in aiding rapid cell division and growth, such as in infancy and pregnancy.
Why is sufficient serum vitamin B12 not a guarantee of sufficient intracellular levels?
Because you also need to check for elevated methylmalonic acid and serum homocysteine levels.
At what serum 25-hydroxyvitamin D level is vitamin D deficiency diagnosed according to many public health institutes?
20 - 30 nmol/l.
Why do most multivitamins have poor bioavailability?
They contain cheap isoforms, resulting in an imbalanced ratio of isoforms in the body.
Has a Tolerable Upper Intake Level been established for β-carotene or other carotenoids?
No, a Tolerable Upper Intake Level has not been established for β-carotene or other carotenoids.
What types of foods are rich in (pro-)vitamin A?
Both fatty protein sources and vegetables.
What is the absolute risk reduction from lowering blood pressure within the normal range for lean, exercising individuals?
The absolute risk reduction is minor.
What additional function do carotenoids have?
They function as antioxidants.
Where is Vitamin K1 primarily found?
Vitamin K1 is found in plants and is commonly the primary source of vitamin K in the diet.
What is the recommended maximum supplementary dose of vitamin C for healthy individuals?
250 mg.
What is the recommended dietary allowance for calcium for most people?
One gram.
Where is Vitamin A primarily found?
In animal foods, especially liver.
How does the benefit of blood pressure reduction from lower sodium intake depend on your current blood pressure?
The benefit depends on your current blood pressure; it is more beneficial for those with higher blood pressure.
Which food has the highest Vitamin A content per 3 oz. serving?
Beef liver with 22,000 IU (6,600 μg).
How can bacteria in your intestines contribute to vitamin K2 levels?
They can convert vitamin K1 to K2.
What is the conversion factor between ng/ml and nmol/l for serum 25-hydroxyvitamin D?
1 ng/ml = 2.496 nmol/l.
What is the Tolerable Upper Intake Level (UL) for preformed Vitamin A per day?
3,000 μg RAE (10,000 IU).
What are B-vitamins?
B-vitamins are a class of related vitamins that function as co-factors or precursors for various metabolic processes, including energy production.
Why do almost everyone in Northern countries benefit from vitamin D supplementation?
Because they see little strong sunlight and there is very little vitamin D in food.
Why is potassium considered an essential micronutrient?
Potassium is essential because it is lost in urine, stool, and sweat, and is necessary for various bodily functions.
What is the recommended general vitamin D3 supplementation dose to ensure sufficient levels in the majority of the population?
4000 IU/d.
Why are vegetarians at risk for vitamin B12 deficiency?
Because vitamin B12 is practically only found in animal foods.
How can you ensure your sodium intake is in the ideal range without obsessing over it?
Consume salt to taste without restriction and avoid very high sodium junk foods.
What is the risk associated with very high levels of the alpha isomer of Vitamin E?
Very high levels of the alpha isomer have been associated with increased cardiovascular disease.
What is the Recommended Dietary Allowance (RDA) of vitamin C for adult women?
75 mg
What additional benefit can getting enough Vitamin D provide?
Getting enough Vitamin D can improve sleep quality.
What is hyponatremia?
A condition in which serum sodium sinks to life-threatening levels.
Which compounds does Vitamin C help produce that are important for connective tissue health, energy production, and brain functioning?
Vitamin C is crucial for the production of collagen, carnitine, tyrosine, norepinephrine, and serotonin.
What is hypertension?
The term for high blood pressure, which increases the strain on blood vessels and the heart.
Is there a risk of vitamin K toxicity with supplementation?
There is virtually no risk of vitamin K toxicity, so supplementation is safe.
Why might it be reasonable to consume a multivitamin?
To make sure you cover all bases and avoid micronutrient deficiencies.
What is the recommended dietary allowance for calcium during periods of growth?
1.3 grams.
What treatments are generally recommended as first-line for exercising individuals with high blood pressure?
Diuretics or angiotensin-converting enzyme (ACE) inhibitors.
What is the maximum daily intake of vitamin D3 that can be taken initially to build up serum levels more rapidly?
Up to 20,000 IU/d.
Why should vitamin D be consumed with a meal containing fats?
Because vitamin D is fat-soluble.
What is the RDA for vitamin B12 for adults?
2.4 μg/day.
What type of vitamin is Vitamin D3 (cholecalciferol)?
Vitamin D3 is a fat-soluble pro-hormone and an essential vitamin.
What did the 2022 meta-analysis find about switching from sodium chloride to potassium chloride?
It found that switching to potassium chloride reduced blood pressure and all-cause mortality considerably.
What is the primary function of Vitamin K in the body?
Vitamin K is required to form coagulation factors, which are essential for blood clotting.
How much vitamin B12 does the body absorb from a 1,000 mcg intake?
The body absorbs only about 13 mcg from a 1,000 mcg intake.
What happens when sodium intake is excessively low?
It activates the renin-angiotensin-aldosterone system (RAAS) and the sympathetic nervous system, creating a stress response similar to chronic stress.
What are the components of sodium chloride?
40% sodium (Na) and 60% chloride (Cl).
What percentage of calcium in the body is found in bones?
99%
How does excess Vitamin A intake affect Vitamin K?
It interferes with Vitamin K absorption.
On average, what effect does salt restriction have on the population?
Salt restriction reduces blood pressure in the population.
What foods are rich in potassium?
Potassium is found in almost all whole foods, notably animal and fish flesh, fruit, vegetables, dairy, tea, and coffee.
How can vitamin E deficiency be diagnosed?
With bloodwork: a serum alpha-tocopherol level below 5 mcg/mL strongly indicates vitamin E deficiency.
What serum level of 25(OH)D is associated with vitamin D intoxication?
Exceeding 200 ng/mL.
Why is supplementing 200+ mcg of folate per day advisable during pregnancy?
Because there’s little toxicity risk and it ensures adequate intake.
What accumulates in the body due to vitamin B12 deficiency?
Methylmalonic acid (MMA) and homocysteine.
How many isoforms or vitamers does Vitamin E have?
Vitamin E has 8 isoforms/vitamers, which include 4 tocopherols and 4 tocotrienols.
Why is bloodwork nearly useless for diagnosing potassium deficiency?
Because almost all potassium stores are intracellular.
Why is it not advisable to consume high doses of vitamin C after exercise?
Because it can suppress inflammation too much, sabotaging muscle growth and exercise adaptations.
Why might lacto-ovo vegetarians have difficulty consuming enough vitamin B12?
Because vitamin B12 is primarily found in animal products, and even foods like cottage cheese, pork loin, eggs, and poultry contain relatively low amounts.
What happens to the bioavailability of vitamin B12 when intake exceeds 2 mcg?
The oral bioavailability of vitamin B12 decreases dramatically above intakes of 2 mcg.
What is a more conservative recommendation for daily Vitamin K intake?
1 mcg per kilogram of body weight.
What is the effect of high doses of vitamin E on training adaptations?
Doses upward of 235 mg of vitamin E may impair training adaptations, including muscle growth, by excessively suppressing inflammation.
What is the relationship between sodium intake and health?
Sodium intake has an optimum curve relation with health: too low and too high intakes can both be harmful.
What are the two natural forms of Vitamin K?
Vitamin K1 (phylloquinone) and Vitamin K2 (menaquinone).
How does skin color affect the time required for optimal vitamin D synthesis from sun exposure?
The darker someone's skin, the more sun exposure they need.
What is a preferable alternative to a very strict low-sodium diet for individuals with high blood pressure?
Blood pressure medication, which can be very effective with an excellent safety profile and practically no major side effects.
Which two groups are notable exceptions that might need to monitor their B-vitamin intake?
Vegetarians and pregnant women.
What are the symptoms of potassium deficiency (hypokalemia)?
Malaise, constipation, muscle weakness, and fatigue.
How is Vitamin D3 produced naturally in the body?
It is produced naturally by the skin after exposure to ultraviolet radiation, particularly UVB, like in sunlight.
How can Vitamin D levels influence strength development?
Vitamin D levels can significantly influence strength development, lean body mass, and injury resistance.
What systems are activated by increased insulin resistance due to low salt diets?
The renin-angiotensin-aldosterone and sympathetic nervous systems.
Is hypercarotenosis harmful?
No, it is harmless and can even make you look extra healthy up to a point.
What is the optimum level of sodium intake for cardiovascular health?
Around 3-5 grams per day.
Which foods contain more than 200 μg of Vitamin K per 100 g?
Broccoli, kale, swiss chard, turnips, watercress greens, collards, spinach, salad greens.
What are the essential functions of Vitamin A?
Vision, cellular differentiation, growth, reproduction, bone development, and immune system functions.
How does high β-carotene intake affect plasma Vitamin E concentrations?
It may decrease plasma Vitamin E concentrations.
Where are carotenoids more commonly available?
In plants.
When is it better to consume vitamin B12 supplements for better absorption?
It's better to consume vitamin B12 supplements while fasted, as bioavailability is lower when taken with a meal.
What is the recommended daily supplementation for vegetarians to ensure adequate vitamin B12 intake?
Vegetarians should supplement a daily B-vitamin complex with at least 100% of the RDI of all B-vitamins and 4 mcg of vitamin B12.
How does sodium affect tissue fluid levels?
Sodium attracts water, so its concentration determines the fluid level in tissues.
Name some of the best food sources of calcium.
Dairy products (milk, cheese, yogurt), selected seafood (salmon, sardines with bones, clams, oysters), selected vegetables (turnips, mustard greens, broccoli, cauliflower, kale), legumes, tofu, and nuts.
Why don't strength trainees generally need to track their B-vitamin intake?
Because B-vitamins are present in most whole foods, particularly animal protein sources.
Which food has the highest vitamin B12 content per 3 oz. serving?
Clams, with 84 μg.
What are some symptoms of acute hypervitaminosis A?
Nausea, vomiting, double or blurred vision, increased intracranial pressure, headache, dizziness, and skin desquamation.
What is a common problem with most multivitamins?
Most multivitamins employ cheap manufacturing methods that result in nutrients that are not bioavailable.
What are the recommended daily allowances (RDA) for Vitamin A for adult men and women?
900 μg RAE (3,000 IU) for adult men and 700 μg RAE (2,310 IU) for adult women.
Why do pregnant women have a high requirement for folic acid (vitamin B9)?
Because it’s important for the neural development of the child.
What is the RDA for Vitamin A for lactating women?
1,300 μg RAE (4,300 IU).
What is the primary take-home message regarding vitamin C intake?
Eat your fruits or veggies and you don’t have to worry about vitamin C.