Congenital malformations

A problem in bone cells itself.

Genetic and environmental factors.

Drugs and chemicals.

An abnormality in the development of an organ.

They are crucial for normal development; disruptions can lead to anomalies.

They can lead to congenital abnormalities or developmental disruptions.

They guide the inheritance of single-gene defects.

Intrinsic factors, such as spina bifida.

A condition characterized by a loss of amniotic fluid.

Good prognosis is associated with appropriate treatment underlining normal structure.

Deformation in the fetus.

Abnormalities in the structure or form of an organism, often present at birth.

Embryogenesis and fetal development.

It could refer to a specific model or version.

A break in the normal development of a body structure due to external or intrinsic factors.

It may refer to a year or a specific time frame.

Non-syndromic malformations.

Abnormalities that occur in association with other defects.

Only one organ or system.

Both mother and fetus have varying susceptibility to teratogens.

Exposure to harmful chemicals during pregnancy can result in congenital anomalies.

They can interact with genetic predispositions.

It refers to self-causing factors in the development of malformations.

It comes from a Greek word meaning 'disordered' and 'form'.

Abnormal organization of cells leading to the development of multiple cysts.

Bone tissue is crucial for structural support and overall health.

Bone disease.

It refers to a type of tissue defect.

They can contribute to the development of these abnormalities.

It can lead to compression of the baby, causing abnormal positioning and shape changes.

A syndrome.

Malformations, disruptions, deformities, or dysplasias that occur during development.

Amniotic band disruption.

VACTERL and other associations.

An abnormal shape or position of a body part due to mechanical forces.

Dysplasia involves changes at the histological level with abnormal organization of tissue and cells, often due to a single gene defect, while malformation can be nongenetic and involves organization of cells within normal levels.

Problems in intrinsic factors such as cell growth and cell functions.

Tissue level.

It is a specific code or identifier.

A condition where one side of the face does not match the other in appearance.

A developmental condition characterized by small or underdeveloped pinna (outer ear).

Factors such as drugs and chemicals that can affect fetal development.

It means 'to follow'.

A condition that can affect the developing fetus, potentially leading to abnormalities.

They can result in severe structural malformations.

Malformations, disruptions, deformities, and dysplasias.

It means the condition remains the same and does not worsen over time.

Renal problems.

Malformations can be caused by nongenetic factors, including environmental influences.

Single abnormalities and multiple abnormalities.

Cleft palates.

Critical periods in human development and the site of action of teratogens.

A condition characterized by low amniotic fluid levels during pregnancy.

To improve clinical management and outcomes.

Excess or deficiency of chromosomal material.

The compression of the baby due to low amniotic fluid.

A causal relationship that has not been identified.

A consistent and recognizable pattern of abnormalities known or thought to be causally related.

It helps in understanding the inheritance patterns of congenital defects.

It indicates that while the shape is altered, the underlying structure remains intact.

It helps in identifying risk factors and preventing congenital abnormalities.

Small mandible, almond-shaped eyes, and small mouth.

A device or mechanism used in various processes, often related to separation or purification.

It disrupts or prevents normal development of hands and fingers.

Fibrous tissue.

Cardiac defects, renal anomalies.

Skeletal dysplasia.

Agents that can cause malformation or abnormal development in an embryo or fetus.

An anomaly known or presumed to cascade from a single anomaly.

The potential effects of any particular teratogen depend on the timing of administration during pregnancy.

Certain drugs can lead to malformations or developmental disruptions in the fetus.

Piere Robin sequence.

It indicates a change in the shape due to external influences.

Vertebral, Anal, Cardiac, Tracheoesophageal, Renal, and Limb anomalies.

Cleft palates, congenital heart defects, polydactyly (extra finger), and osteogenesis imperfecta.

Amniotic rupture.

David Smith in the 1960s to describe the study of human congenital malformations and patterns of birth defects.

Congenital heart defects.

It refers to structural anomalies that can be identified in an individual.

Veterbral malformations.

Not covered by skin and covered by skin.

Genetic defects and environmental factors.

Agents that can cause a birth defect by interfering with normal embryonic or fetal development.

Abnormalities that occur in isolation.

Congenital abnormalities.

Factors that can affect the developing embryo, either genetically or acquired.

Alterations in the structure of chromosomes that can lead to developmental anomalies.

Changes in shape and potential congenital abnormalities.

Conditions such as diabetes, infections, and autoimmune diseases.

It describes all types of structural abnormalities that can occur in an embryo, fetus, or newborn.

An abnormal organization of cells within a tissue.

They affect external organs and external appearance.

Both lead to abnormal development at the tissue level.

After birth, within 2-3 weeks.

Abnormal organization of cells.

During fetal life and after birth.

External factors and intrinsic factors.

They are a specific ear shape that can be associated with certain developmental conditions.

They can result in isolated congenital abnormalities.

It gives an abnormal shape.

A structural defect resulting from an abnormal development process.

No, not all malformations are genetic; some are due to non-genetic factors.

Potter sequence.

Through inherited genetic mutations or chromosomal abnormalities.

It helps in understanding patterns and potential underlying causes.

Dysplasia refers to changes at the histological level where tissue and cells are abnormally organized, often linked to a single gene defect.

They can be due to genetic factors, environmental influences, or a combination of both.

Damage by infection.

They can interfere with fetal development.

Alterations in the number or structure of chromosomes.

Disruption.

They are specific times when the developing organism is particularly sensitive to environmental influences.

Early during the development of the fetus.

External factors, specifically mechanical forces.

A defect resulting from the breakdown of an originally normal structure.

They can lead to various health issues and developmental delays.

They can lead to multiple congenital anomalies that have a single cause.

Environmental factors can contribute to the development of congenital anomalies.