In Limbic-Predominant Encephalopathy, there are usually no other coexistent ___.
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antibodies
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In Limbic-Predominant Encephalopathy, there are usually no other coexistent ___.
antibodies
CASPR2 antibodies are linked to ___, a condition where the immune system mistakenly attacks the brain.
autoimmune encephalitis
CASPR2 antibody disease primarily affects older males, typically in their ___ and ___.
sixties, seventies
___ shows encephalopathy in patients with CASPR2 antibody disease.
EEG
Morvan Syndrome symptoms include severe autonomic dysfunction, ___, peripheral nerve hyperexcitability, and psychiatric symptoms.
insomnia
In diagnostic investigations for CASPR2 antibody disease, ___ and ___ are often normal.
CSF, MRI
The male-to-female ratio of CASPR2 antibody disease is about :.
9:1
Needle EMG detects peripheral nerve ___, which is a specific feature of CASPR2 antibody disease.
hyperexcitability
Immunotherapies are more effective in patients with ___ antibodies compared to those with CASPR2 antibodies.
LGI1
The disease typically develops over several ___, which can overlap with more rapid neurodegenerative conditions like Creutzfeldt-Jakob disease.
months
Neuropathic pain in Morvan syndrome is possibly due to small fiber ___.
neuropathy
Higher titers in ___ help reduce false positives in antibody testing for CASPR2 antibody disease.
CSF
Limbic-Predominant Encephalopathy symptoms include ___, ___, and ___.
disorientation, amnesia, seizures
Approximately ___% of patients with Morvan Syndrome have a thymoma.
25
Movement disorders associated with CASPR2 antibody disease include ataxia, myoclonus, tremor, paroxysmal ataxia, and orthostatic leg ___.
myoclonus