What is the invasive form of amoebae that can spread to other parts of the body?
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Invasive trophozoite.
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What is the invasive form of amoebae that can spread to other parts of the body?
Invasive trophozoite.
What type of cyst is resistant to gastric acidity in intestinal amoebae?
Quadrinucleate cyst, which means it has four nuclei.
What is the typical manifestation of intestinal amebiasis?
Amoebic dysentery, mostly presenting as diarrhea.
What is unique about Entamoeba moshkovskii?
It is primarily a free-living amoeba and can survive at room temperature and between 0 - 41°C.
What symptoms may present in children with intestinal amebiasis?
Bloody diarrhea, fever, and abdominal pain.
What is an ameboma?
A mask-like lesion with abdominal pain and a history of dysentery, benign but can be mistaken for carcinoma.
What is the primary reservoir host for Balantidium coli?
Pigs.
What is the primary difference in movement between E. histolytica and E. coli trophozoites?
E. histolytica moves unidirectionally and progressively, while E. coli is sluggish and non-progressive.
What are Charcot-Leyden crystals associated with?
They are found microscopically in the stool in cases of amoebic dysentery.
What are the two organisms involved in parasitology?
The parasite and the host.
What is drug resistance?
Genetically transmitted loss of susceptibility to a drug in a previously sensitive worm population.
What is the appearance of Endolimax nana cysts?
They have 4 eccentric nuclei and look like dots, referred to as 'cross-eyed cysts'.
What is the causative agent of balantidiasis?
Balantidium coli.
What is co-infection?
Simultaneous infection of a host by two or more parasites.
What is the size range of Entamoeba coli cysts?
10 – 35 microns.
What defines targeted treatment?
Group-level deworming for a risk group defined by age, gender, or social characteristics, regardless of infection status.
What is the shape of Iodamoeba butschlii?
Resembles a 'basket of flowers'.
What is the incubation period in parasitology?
The period between infection and the evidence of symptoms.
What are the CSF examination findings for Naegleria fowleri?
Cloudy to purulent, neutrophilic leukocytosis, elevated protein, and low glucose.
What is the most common extraintestinal manifestation of amebiasis?
Amoebic liver abscess.
What severe condition can Acanthamoeba spp. cause in immunocompromised patients?
Granulomatous Amoebic Encephalitis (GAE).
What are biological vectors?
Organisms that host the parasite inside their body and are necessary for the parasite's development.
What is the primary disease caused by Naegleria fowleri?
Fatal Primary Amoebic Encephalitis (PAM).
What causes ulceration in Balantidium coli infections?
Hyaluronidase secreted by trophozoites.
What does a pandemic refer to?
A disease that has been disseminated in an extensive area of the world.
What is selective treatment in parasitology?
Individual-level deworming based on diagnosis or presumptive grounds.
What are the modes of transmission for Naegleria fowleri?
Oral and intranasal routes while swimming in contaminated pools, rivers, and lakes.
What does coverage refer to in parasitology?
The proportion of the target population reached by an intervention.
What is the size of Endolimax nana?
It is known as the 'smallest amoeba'.
What is Acanthamoeba spp. known for?
It is a ubiquitous, free-living ameba with thorn-like appendages.
What is the diagnostic stage for amoebiasis?
Identification of the cyst or trophozoite.
What is mutualism?
A symbiotic relationship beneficial to both organisms.
What is Naegleria fowleri commonly referred to as?
'Brain-eating amoeba'.
What are endoparasites?
Parasites that live inside the body of the host.
What is an epidemic?
A sudden outbreak or rise of incidence in a human population above what is normally expected.
What are some key practices to prevent contamination of food and water?
Wash hands, ensure sanitary disposal of human feces, improve access to clean drinking water, and practice good food preparation.
What is the motility of Entamoeba coli?
Sluggish, not progressive and non-directional.
What is parasitology?
An area of science that studies organisms living on or within another organism.
What is the significance of Entamoeba gingivalis?
Found in the mouth, abundant in oral diseases, and does not have a cyst stage.
What is a key feature of the nucleus in Endolimax nana?
Not visible, but has a large, centrally located karyosome surrounded by small granules.
What is the size range of E. histolytica cysts?
10 to 15 μm.
What is the relationship between a parasite and its host?
The parasite benefits while the host is usually harmed.
What is the laboratory diagnosis for Acanthamoeba keratitis?
Demonstration of cysts in corneal scrapings by wet mount and culture.
What is a common method for laboratory diagnosis of amoebiasis?
Direct fecal smear.
What does cumulative prevalence indicate?
The percentage of individuals in the population infected with at least one parasite.
What is disease elimination?
Reduction to zero of incidences of a specified disease in a defined geographical area, requiring continued intervention.
What factors determine the intensity of parasitic infection?
Topography, social conditions, age, hygienic measures, sewage disposal, and water supply.
What are examples of bacteria that can cause bacillary dysentery?
Salmonella, Shigella, Campylobacter spp., Yersinia spp., and Enteroinvasive E. coli.
What are the signs/symptoms of bacillary dysentery?
Fever and usually vomiting, offensive odor of feces, often watery and bloody stools.
How does Naegleria fowleri penetrate the body?
It can penetrate the nasal mucosa during swimming and travels through the olfactory nerve.
What is protozoology?
The study of protozoans, which are small, unicellular organisms.
How is efficacy defined in the context of drug treatment?
The effect of a drug against an infective agent under ideal experimental conditions.
How can Acanthamoeba spp. be transmitted?
Through aspiration or nasal inhalation from contaminated water or direct invasion of the eye.
What is the drug of choice for invasive amebiasis?
Metronidazole.
What are common sources of soil-transmitted parasites?
Contaminated soil and water, often due to lack of sanitary toilets.
What are the two vegetative forms of Naegleria fowleri?
A trophozoite (ameba) form and a flagellate (swimming) form.
What is a definitive host?
The host that harbors the adult and sexually mature form of the parasite.
What is the difference between direct and indirect measurement of infection intensity?
Direct involves counting expelled worms during treatment, while indirect involves counting helminth eggs excreted in feces.
What is the difference between pathogenic and non-pathogenic organisms?
Pathogenic organisms cause disease, while non-pathogenic do not.
What is the process of infection?
The establishment of an infective agent in the host.
What is lytic necrosis?
Destruction of tissues due to secretory and excretory products from parasites.
How many nuclei can Entamoeba coli cysts contain?
8 or more, and may become hypernucleated with 16 - 32 nuclei.
What is Iodamoeba butschlii known for?
Its affinity to iodine and large glycogen vacuole that stains deeply with iodine.
What is the incubation period for amebiasis?
It can range from four days to four months.
What are the laboratory diagnosis methods for Naegleria fowleri?
CSF examination, wet film examination of CSF, autopsy, culture, and molecular diagnosis (PCR).
What does helminthology focus on?
The study of worms, which are larger, multicellular organisms.
What is the difference between efficacy and effectiveness?
Efficacy measures performance under controlled conditions, while effectiveness measures performance in real-world conditions.
What is parasitism?
A relationship where the parasite lives on or in the host, harming it.
What is the goal of environmental sanitation?
To reduce environmental health risks through safe disposal of waste and control of disease vectors.
What are the signs and symptoms of balantidiasis?
Similar to amoebic dysentery.
What are the common portals of exit for parasites?
Stool, urine, sputum, blood, tissue aspirates, biopsy, orifice swab, and discharge.
Define endemic disease.
A disease with a steady moderate level in a human population within a geographical area.
What does incidence refer to in epidemiology?
The number of new cases of infection appearing in a population in a given period of time.
What is egg reduction rate in the context of deworming?
The percentage fall in egg counts after deworming based on stool or urine examination.
What is Entamoeba coli?
A commensal and harmless inhabitant of the colon.
What is the onset of amoebic dysentery?
Gradual.
What is universal treatment?
Population-level deworming where the entire community is treated irrespective of age, gender, or infection status.
What is the motility characteristic of Endolimax nana?
Sluggishly progressive with hyaline pseudopodia.
What is a common inclusion found in E. histolytica trophozoites?
Red blood cells (RBCs).
What is autoinfection?
When an infected individual becomes their own direct source of infection.
What is morbidity control?
Avoidance of illness caused by infections, achieved by periodic deworming of at-risk individuals or groups.
What is the infective stage of Balantidium coli?
Cyst.
What are ectoparasites?
Parasites that live outside the body of the host.
What is disease eradication?
Permanent reduction to zero of worldwide incidences of infection caused by a specific agent.
What are initial symptoms of PAM caused by Naegleria fowleri?
Fever, headache, sore throat, nausea, and vomiting.
What is a carrier in the context of infection?
An individual that harbors a pathogen without showing symptoms.
What is epidemiology in the context of parasitology?
The science concerned with the propagation of disease, studying patterns, distribution, and occurrence.
What is deworming?
The use of anti-helminthic drugs in an individual or public health program.
What distinguishes Entamoeba dispar from E. histolytica?
Morphologically similar but has different DNA and RNA.
What type of ulceration is associated with intestinal amebiasis?
Flask-shaped ulcer.
What is the most important tissue invading factor produced by amoeba?
Cystein proteinase.
What is the pre-patent period?
The biological incubation period between infection and the demonstration of infection.
What is medical entomology concerned with?
Insects and arthropods that transmit parasites.
What are the morphological features of Balantidium coli?
Has trophozoite and cyst stages, cytostome for food entry, cytophyge for waste excretion, and two dissimilar nuclei.
What is the purpose of percutaneous drainage in amoebic liver abscess?
To provide prompt relief of severe pain in patients not responding to metronidazole.
What is prevalence in parasitology?
The percentage of individuals in a population estimated to be infected with a particular parasite at a certain time.
What is a reservoir host?
An animal that harbors the same parasite as humans, allowing the life cycle to continue.
What are the types of life cycles in parasites?
Simple or complicated, with complicated cycles involving multiple intermediate hosts.
What is traumatic damage in parasitic infections?
Damage caused when parasites invade the skin and other tissues, leading to destruction.
How is cure rate expressed in deworming?
As the percentage of previously positive subjects found to be egg-negative after examination.
What is superinfection?
When an already affected individual is further infected with the same species, leading to massive infection.
What does IEC stand for in health education?
Information-Education-Communication, a strategy to encourage healthy life practices.
What is environmental management in the context of parasitology?
Planning and monitoring activities to modify environmental factors to reduce vector propagation and human contact with infective agents.
What are some prevention methods for Naegleria fowleri?
Frequent cleaning, chlorination, and salination.
What are the common portals of entry for parasites?
By mouth, skin penetration, intranasal, transplacental, transmammary, and sexual intercourse.
How are parasites classified scientifically?
According to the International Code of Zoological Nomenclature, with Latinized names.
What are the life stages of a parasite?
Ova, egg, larva, trophozoite, cyst, and adult.
What are tissue reactions in parasitic infections?
Cellular proliferation and white cell infiltration at the site of the parasite.
What is the drug of choice for treating balantidiasis?
Tetracycline.
What are mechanical vectors?
Organisms that transport the parasite without hosting it or allowing its development.
How is intensity of infection measured?
By the number of worms per infected person, also known as worm burden.
What diagnostic sign is associated with meningitis in PAM?
'Kernig’s sign', where the patient cannot fully straighten their leg when the hip is flexed.
What characterizes a sporadic disease?
It appears only occasionally in one or a few members of the community.
What are the modes of reproduction in parasites?
Sexual (oviparous, ovoviviparous, larviparous) and asexual (binary fission, parthenogenesis).
How do parasites deprive hosts of essential nutrients?
By competing with the host for available vitamins and nutrients.
What causes toxic allergic phenomena in parasitic infections?
Proteins or metabolites from parasites that induce hypersensitivity reactions.
What are common treatment options for parasitic infections?
Antiparasitic medications, dietary changes, vitamin supplements, fluid replacement, blood transfusion, and bed rest.