What is red-green colorblindness?
Click to see answer
A sex-linked recessive trait characterized by the inability to see red and green.
Click to see question
What is red-green colorblindness?
A sex-linked recessive trait characterized by the inability to see red and green.
Do sons inherit their father's sex-linked traits?
No, fathers pass their X chromosome (with the trait) to daughters and the Y chromosome to sons.
Who is known for conducting hybridization experiments in garden peas?
Gregor Mendel.
What is the genotype of the F1 generation in the example provided?
Tt.
What are the two types of allele combinations in diploid organisms?
Homozygous and heterozygous.
What restores the diploid number of chromosomes in offspring?
The fusion of haploid gametes during fertilization.
What is the focus of Fig. 4?
Examples of crosses between rabbits with different coats.
What is the physical basis of Mendelian inheritance?
The behavior of chromosomes.
What condition is the man diagnosed with after taking primaquine?
Glucose 6-phosphate deficiency.
How does random fusion of gametes contribute to genetic variation?
It creates different combinations of alleles in the organism.
What happens when a male with colorblindness has a daughter?
The daughter will become a carrier if her other X chromosome carries a normal allele.
Why must we differentiate between males and females for sex-linked traits?
Because the alleles are located on the sex chromosomes, and gender itself is a phenotypic difference.
What do homologous chromosomes have in common?
The alleles occupy the same position on separate chromosomes.
What does a Punnett square represent?
All possible outcomes of a genetic cross.
What is the phenotype ratio of tall to short plants in the F2 generation?
3:1.
What genotype represents a tortoise-shell cat?
X^B X^G.
What two pairs of alleles determine seed characters in Pisum sativum?
Green and yellow; round and wrinkled.
In the first cross, what are the phenotypes of the parents?
Yellow round and green wrinkled.
What is Dihybrid Inheritance?
Inheritance of 2 pairs of contrasting characteristics simultaneously (i.e., 2 genes).
How does genotype affect phenotype?
Genotype determines the traits expressed in the phenotype.
What is the phenotypic ratio obtained when a dihybrid individual is crossed with a double homozygous recessive individual?
1:1:1:1.
Why is the allele coding for a functional protein usually dominant?
Because it produces some functional protein in heterozygous cells, which is usually sufficient for the desired effect.
What is the significance of the allele inheritance in blood group determination?
A child inherits one allele from each parent, determining their blood group.
What is codominance?
A genetic scenario where both alleles in a heterozygote are fully expressed.
What is the homogametic sex?
The sex that produces only one kind of gamete (e.g., females with XX genotype).
What are the alleles for yellow and green seeds?
Y = allele for yellow seed, y = allele for green seed.
What are the dominant and recessive alleles for resistance to race 22?
A (dominant) for resistance and a (recessive) for susceptibility.
What type of organism is being studied in the crosses?
Rabbits.
What mechanisms during meiosis ensure genetic variation?
Crossing over and independent assortment.
From whom do males obtain their only X chromosome?
From their mothers.
What type of trait is glucose 6-phosphate deficiency?
A sex-linked recessive trait.
How should alleles for sex-linked traits be represented?
They must be written on the sex chromosome.
What are two examples of sex-linked traits?
Red-green color blindness and hemophilia.
What is a dihybrid cross?
A genetic cross involving two traits.
What is the progeny distribution for the first cross?
138 yellow round, 143 yellow wrinkled, 137 green round, 142 green wrinkled.
What phenotypic ratio is typical of a Mendelian dihybrid cross?
9:3:3:1.
What are the male and female gametes represented in the Punnett square?
Male: T, t; Female: T, t.
What traits were observed in the F1 progeny?
All round and yellow, indicating these traits are dominant.
What are alleles?
Alternative forms of a gene, each with a slightly different nucleotide sequence, coding for different forms of the same trait.
What is the genotype of the colourblind female in the third example?
XcXc.
How many alleles does a diploid cell contain for the same gene?
Two alleles, one on each of the pair of homologous chromosomes.
What type of organism has two copies of each chromosome?
A diploid organism.
Why are sex-linked recessive traits more common in men than women?
Men have no corresponding allele on the Y chromosome to mask the effect of the recessive allele on the X chromosome.
Which chromosome carries more genes related to sex-linked traits?
The X chromosome carries many such genes, while the Y chromosome has very few.
What are the two main types of genetic expressions?
Genotypes and phenotypes.
How many classes of coat color would you find in male cats?
Two classes: black and ginger.
What are the genotypes of parents with blood groups A and B?
IAIO (blood group A) and IBIO (blood group B).
What is the chromosome number in each gamete?
Each gamete contains only half the number of chromosomes (haploid).
What is the progeny distribution for the second cross?
176 yellow round, 0 yellow wrinkled, 60 green round, 0 green wrinkled.
What percentage of gametes carry the Y allele?
50%.
What is the genotypic ratio for the 3:1 Monohybrid Ratio?
1 homozygous dominant : 2 heterozygotes : 1 homozygous recessive.
How are phenotype and genotype of the offspring related?
They must be co-related.
What is a key characteristic of traits that do not follow Mendelian inheritance?
They do not give the expected 9:3:3:1 ratio in certain crosses.
How many phenotypes were found in the F2 generation?
Four phenotypes: two parental and two new combinations.
What is a dominant allele?
An allele whose characteristics are expressed in the phenotype even in the presence of an alternative allele.
What is the typical monohybrid ratio observed for each trait in the F2 generation?
A ratio of 3:1.
What is the dominance order of the alleles for coat color in Himalayan rabbits?
C > Cch > Ch > c.
What is the purpose of a Dihybrid Test Cross?
To determine the genotype of an organism showing the dominant phenotypes for 2 traits.
What is the significance of traits at the population level?
Traits promote survival or reproduction and are important in evolution.
What is epistasis?
When two genes interact to produce one phenotypic outcome.
What are the different modes of inheritance mentioned?
Autosomal Dominant, Autosomal Recessive, Sex-linked Dominant, Sex-linked Recessive.
What trait is being compared in the rabbit crosses?
Coat color.
What type of cells are formed after meiosis?
Gametes, which are haploid.
What are sex-linked traits?
Characteristics where the genes involved are found on the sex chromosome, and their inheritance depends on the sex of the organism.
What is the genotype of Variety B of flax?
aaBB (susceptible to race 22 and resistant to race 24).
What role do proteins play in phenotype expression?
Proteins control phenotype as enzymes, pumps, transporters, motors, hormones, or structural elements.
Is it possible to find a tortoise-shell male cat?
No, because males have only one X chromosome.
What ultimately determines phenotypic expression?
The genotype.
What is a locus?
The specific location of a gene on a chromosome.
What must be true about gametes in terms of alleles?
Each gamete can only contain 1 copy of each gene (1 allele).
What is a key difference in F1 results between sex-linked and autosomal linked genes?
Reciprocal crosses give different F1 results for sex-linked genes, while they give the same F1 results for autosomal linked genes.
What is the fur color pattern of Himalayan rabbits?
White fur with black fur on the ears, noses, feet, and tails.
How many copies of the allele does each gamete carry?
Only 1 copy of the allele compared to the original cell.
How many different combinations of alleles are possible from a double heterozygote?
Four different combinations.
What happens to the enzyme tyrosinase at temperatures above 33°C?
The enzyme is denatured, resulting in light/white fur.
Why can't test-crosses be performed in humans?
Because we cannot perform test-cross, reciprocal cross, and back cross to determine genotypes.
What do shaded symbols in a pedigree represent?
Traits that are expressed.
Why are the extremities of Himalayan rabbits black?
Because the temperature is lower there than on the main body.
What is the genotype for males in humans?
XY.
What is the genotype of the double heterozygote parent in the example?
RrYy.
What is the phenotypic ratio in the F2 generation of shorthorn cattle?
1 red : 2 roan : 1 white.
What are the three alleles for the ABO blood group?
I A, I B, and I O (or i).
What is the significance of blood group AB?
It is the universal recipient.
What is the genotype of a heterozygote example?
Yy.
What is Mendel's first law?
Law of Segregation.
What is the genotype of Variety A of flax?
AABb (resistant to race 22 and susceptible to race 24).
What allele represents tallness in the genetic diagram?
T (dominant allele).
What occurs in Anaphase II of meiosis?
Separation of sister chromatids.
What does it mean that both offspring are carriers in the first example?
They carry the allele for colourblindness but are phenotypically normal.
What are sex chromosomes?
Chromosomes that determine the sex of the organism.
What are autosomes?
Chromosomes that do not determine the gender.
What is the difference between dominant and recessive alleles?
Dominant alleles express their traits even in the presence of a recessive allele, while recessive alleles only express their traits when homozygous.
What is present in each gamete according to Mendel's Law?
1 copy of the allele for each gene.
What are the four levels of the relationship between genotype and phenotype?
Molecular, Cellular, Organismal, and Population levels.
What are the four alleles of the gene C in Himalayan rabbits?
C, Cch, Ch, and c.
What is a test cross?
A cross between an organism with an unknown genotype showing dominant characteristics and a homozygous recessive individual.
How does the cellular level affect phenotype?
The presence of specific proteins affects the structure and biochemistry of the cell.
What are the dominant and recessive alleles for resistance to race 24?
B (dominant) for resistance and b (recessive) for susceptibility.
What genotype corresponds to the chinchilla coat in Himalayan rabbits?
CchCch or CchCh.
How can the phenotype be influenced?
By the genotype of the organism and environmental factors.
How can a couple with normal vision have a colorblind child?
Both parents could be carriers of the colorblind allele.
Is it possible for a colorblind girl to be born?
Yes, if both parents are carriers of the colorblind allele.
What happens in the absence of factor 8 in hemophiliacs?
It results in failure of blood to clot, causing slow and persistent bleeding.
What increases the frequency of hemophilia expression?
Inbreeding, such as in European royal families.
What is the significance of the F1 generation in this genetic cross?
They produce pink flowering offspring.
What does allele I O (or i) cause in terms of antigens?
No production of antigens on red blood cells.
What are the two laws discovered by Mendel?
Law of Segregation and Law of Independent Assortment.
What does a monohybrid cross involve?
The inheritance of one single pair of contrasting characters.
What happens during Anaphase I of meiosis?
Separation of homologous chromosomes.
What was the conclusion of the breeder regarding the black-spotted bitch's genotype?
The breeder concluded that the bitch was homozygous for the allele for black spots, but this conclusion is incorrect because the black-spotted bitch could be heterozygous.
What is a gene?
A specific length of DNA that codes for a polypeptide and occupies a position on a chromosome known as a locus.
What is the main idea of Non-Mendelian Genetics?
The inheritance pattern of many characteristics does not follow the ratios predicted by Mendel’s Laws.
What is the progeny distribution for the third cross?
223 yellow round, 247 yellow wrinkled, 75 green round, 86 green wrinkled.
What are sex-linked genes?
Genes found on the sex chromosomes, affected by the sex of the organism.
What ratio was obtained for the F2 generation?
A 9:3:3:1 ratio.
What is a genotype?
The genetic makeup of an organism or set of alleles of an organism.
What is the first step to determine the genotypes of the parents in the crosses?
Analyze the progeny results to identify dominant and recessive traits.
What are some situations not covered by Mendel's Laws?
Not all organisms are diploid, one gene may have more than two alleles, some alleles do not show a dominant-recessive relationship, and alleles may not assort independently.
Which alleles are dominant in the context of the given crosses?
Yellow and round are dominant traits.
Why is a homozygous recessive individual used in a test cross?
To ensure that all gametes from this individual contain a recessive allele, preventing masking of any recessive allele in the organism with the unknown genotype.
What is gametogenesis?
The formation of haploid gametes by diploid germ cells through meiosis.
What is an example of a trait studied through pedigrees?
Hypercholesterolemia, which is considered autosomal dominant.
What does independent assortment mean in genetics?
The alleles of different genes are inherited independently of each other.
What does 'autosomal' mean in the context of inheritance?
The gene is carried on the autosomes or non-sex chromosomes.
What is the probability of a child being red-green colorblind if the mother has normal vision and the father is colorblind?
0.50 (50%).
What is the difference between sister chromatids and non-sister chromatids?
Sister chromatids are identical, while non-sister chromatids may carry different alleles.
What is codominance?
The phenomenon in a heterozygote where both alleles are expressed in the phenotype.
What is the genotype for heterozygous condition in sickle-cell anemia?
Hb A Hb S.
What are the alleles for fur color in cats?
B (black fur) and G (ginger fur), which are codominant.
In a monohybrid cross, what is the phenotypic ratio of the offspring?
3:1.
What is a gene?
A length of DNA that codes for a protein.
What must be indicated in sex-linkage studies?
The sex chromosomes (XX and XY) and the dominant and recessive alleles using appropriate superscript letters.
What is the outcome of gamete formation in a diploid organism?
Half of the gametes carry one allele, and the other half carry the other allele.
What is the genotype of the short plant in the monohybrid cross?
tt.
How can a man transmit a sex-linked trait to his grandson?
Through his daughter, as she can inherit the trait from her father.
What does the term 'gene locus' refer to?
The position occupied by the gene on the chromosome.
What is the inheritance pattern of an X-linked trait typically observed?
Mother to son inheritance.
What does the presence of only one type of F1 hybrid indicate about the parental varieties?
They must be in the gene loci that determine specific resistance.
What is the purpose of a test cross?
To determine if an organism showing a dominant trait is homozygous dominant (AA) or heterozygous (Aa).
What occurs at the molecular level of genotype-phenotype relationship?
Gene transcription and translation leading to the production of a particular protein.
What phenotype does allele C produce in Himalayan rabbits?
Full coat color (all hair agouti).
What is the significance of meiosis in inheritance?
Meiosis produces gametes, which carry genetic information from one generation to the next.
What occurs when the temperature is below 33°C for Himalayan rabbits?
The enzyme is active, and melanin is produced, resulting in black (or brown) fur.
What are the two possible genotypes for an organism showing a dominant trait?
Homozygous dominant (AA) or heterozygous (Aa).
What is sex linkage?
When a gene is located on a sex chromosome rather than an autosome.
What is the parental generation in genetic crosses?
The generation of individuals of different genotypes crossed to produce offspring.
What genotype corresponds to the albino coat in Himalayan rabbits?
cc.
What is the sex of a colorblind child born to normal vision parents?
The child must be male.
What does pure bred or true bred mean?
An organism that is homozygous for a particular characteristic or trait.
How do heterozygotes appear in incomplete dominance?
They show an intermediate trait between the homozygous dominant and homozygous recessive phenotypes.
What is the definition of multiple alleles?
A trait controlled by a gene with 3 or more alleles, of which only 2 may occupy the same locus on homologous chromosomes.
What is the significance of blood group O?
It is the universal donor.
What is the passage of information from parent to offspring called?
Inheritance.
What is the genotype of the colourblind male in the first example?
XcY.
What determines the color of spots in Dalmatian dogs?
A gene with two alleles, where the black allele is dominant and the brown allele is recessive.
What does the F1 hybrid of the two varieties represent?
A double heterozygote (AaBb) resistant to both races of the fungus.
What does the dominant allele code for in flower color?
A functioning enzyme that converts a white pigment into a red pigment.
What is the phenotypic ratio of offspring from a cross between blood group A and blood group B?
1:1:1:1 (AB:A:B:O).
What is the result of the recessive allele in flower color?
It codes for a non-functional enzyme, resulting in white flowers.
How can the environment influence gene expression?
By affecting the organism's external and internal environment, such as hormones and metabolism.
What is the probability of each gamete being fertilized?
Each gamete has an equal probability of being fertilized by another gamete.
What is the progeny distribution for the fourth cross?
371 yellow round, 0 yellow wrinkled, 0 green round, 0 green wrinkled.
Where were sex-linked traits first discovered?
In Drosophila, when inheritance of some characteristics varied with the sex of the parent and offspring.
What allele do all Himalayan rabbits have?
The ch allele, which codes for a temperature-sensitive form of the enzyme tyrosinase.
What is incomplete dominance?
A genetic scenario where the phenotype of heterozygotes is intermediate between the phenotypes of the two homozygotes.
What are the possible combinations of alleles from a double heterozygote?
RY, Ry, rY, ry in equal proportions.
What is codominance?
A situation where alleles of a gene do not have a clear dominant-recessive relationship.
What are the possible outcomes when crossing unspotted and spotted plants?
Sometimes all offspring have unspotted petals, and sometimes half have spotted and half have unspotted petals.
What does Mendel's Second Law state?
Any one pair of characteristics may combine with either one of another pair.
What is a phenotype?
All the characteristics of an individual that are expressed, including physical, physiological, and behavioral traits.
What happens during meiosis according to modern genetics?
The segregation of alleles of one gene pair is independent of the separation of alleles of other gene pairs.
What genotype corresponds to the Himalayan coat in Himalayan rabbits?
ChCh or Chc.
What are the three phenotypes in a honey bee colony?
Queen bees, worker bees, and drones.
What is the ratio of round seeds to wrinkled seeds in the F2 generation?
9/16 round seeds to 7/16 wrinkled seeds.
What is the F2 generation?
The second filial generation produced by crossing two F1 organisms or by selfing.
Can you work out results for other test crosses for round yellow parents who are not double heterozygotes?
Yes, by determining the genotype of the round yellow parent and crossing it with the double homozygous recessive.
What type of genetic inheritance is demonstrated in snapdragons?
Incomplete dominance.
What are the three phenotypes of sickle-cell anemia?
Homozygous normal, homozygous sickle-cell, and heterozygous condition.
Which alleles are codominant in the ABO blood group?
Alleles I A and I B.
What does the Law of Segregation state?
Only one of a pair of alleles can be represented in a single gamete.
During which phase of meiosis do alleles segregate?
Anaphase I.
What is the genotype of the tall plant in the monohybrid cross?
TT.
What is a reciprocal cross?
A cross where the same genetic features are used but the sexes are reversed for each cross.
What does a double heterozygote carry?
Two pairs of homologous chromosomes, each carrying a different gene.
Why are reciprocal crosses important in sex-linkage studies?
They help evaluate the importance of parental sex on the inheritance of a given characteristic.
What results from the random arrangement of homologous chromosomes during Metaphase 1?
Different combinations of alleles in the gametes.
What traits did Mendel investigate in his genetic diagram?
Seed shape (round vs wrinkled) and seed color (green vs yellow).
What is the result of crossing a homozygous dominant organism with a homozygous recessive organism?
The 1:1 Monohybrid Test-Cross Ratio.
What must a female inherit to express colorblindness?
Two copies of the recessive alleles (homozygous recessive).
Why is resistance considered a dominant trait in this context?
Because the F1 is resistant to both race 22 and race 24.
What is the primary method used to study human genetics?
The study of pedigrees.
What is the significance of reciprocal crosses in sex-linked inheritance?
They give different results in the F1 generation.
Which alleles are dominant in Mendel's investigation?
R is dominant over r and Y is dominant over y.
What is the ratio of phenotypes in the F1 generation from the third example?
1:1.
What does each gamete contain according to the Law of Segregation?
One allele of each gene.
In a genetic diagram, how is a recessive allele represented?
By a lower case letter.
What experiment did Sturtevant conduct to demonstrate color change in Himalayan rabbits?
He shaved a small area of fur and applied ice packs, resulting in black fur regrowth.
What does Rh+ and Rh- signify in blood types?
Rh+ indicates blood with the Rhesus factor, while Rh- indicates blood without the Rhesus factor.
What is the F1 generation?
The first filial generation produced by crossing two parental stocks.
What is the genotype of the double homozygous recessive parent in the example?
rryy.
What are the genotypes of the red and white flowered snapdragons?
Red: C_R C_R; White: C_W C_W.
What is the phenotypic ratio of the F2 generation from pink snapdragons?
1 red : 2 pink : 1 white.
How do heterozygotes appear in codominance?
They show the characteristics of both alleles.
What is the genotype for homozygous normal in sickle-cell anemia?
Hb A Hb A.
How many classes of coat color would you find in female cats?
Two classes: black and ginger, plus tortoise-shell.
What are the phenotypes of the F1 generation from the first example?
Female with normal vision and Male with normal vision.
What is the genotype of a double heterozygote example?
YyRr.
Give an example of Dihybrid Inheritance.
Tall plants with pink flowers vs Short plants with white flowers.
What is the phenotypic ratio obtained when both parents are homozygous for a trait in monohybrid inheritance?
The 3:1 Monohybrid Ratio.
What does the Law of Independent Assortment state?
The inheritance of 2 different characters is independent of each other.
How can offspring with blood group O be produced from parents with blood groups A and B?
Both parents must be heterozygous, contributing one IO allele each.
What did Mendel's experimental work primarily involve?
Crossing pea plants that displayed complete dominance.
What are the alleles for round and wrinkled seeds?
R = allele for round seed, r = allele for wrinkled seed.
What is the genotypic ratio of the offspring when a heterozygote is crossed with a homozygous recessive organism?
1 heterozygote : 1 homozygous recessive.
What does homozygous mean?
A diploid condition where both alleles for a particular gene are identical.
What happens when two plants with spotted petals are crossed?
The offspring always have spotted petals.
What is the gamete formation ratio in humans?
1:1, indicating equal probability of having a boy or a girl.
What does multiple alleles refer to?
A single gene having more than two different alleles.
What is the genotype for females in humans?
XX.
What is an example of multiple alleles in humans?
The human blood group ABO.
Can blood groups prove paternity?
No, but they can show that an individual could not possibly be the father.
What are the gametes produced by the colourblind female in the third example?
Xc and Xc.
What is the heterogametic sex?
The sex that produces two types of gametes (e.g., males with XY genotype).
What are the possible genotypes of the F1 generation from the third example?
XcYC and XcY.
What is a recessive allele?
An allele whose characteristics are only expressed in the phenotype in the presence of another identical allele (homozygous condition).
What determines the traits of an organism at the organismal level?
The characteristics of cells, such as the production of pigments.
In a genetic diagram, how is a dominant allele represented?
By an upper case letter.
What type of organism is used in a Dihybrid Test Cross?
A double homozygous recessive organism.
What is an example of monohybrid inheritance involving fruit flies?
Long wing vs. vestigial wing.
What is an example of a dominant and recessive allele in plants?
Allele P for purple stem is dominant over allele p for green stem.
What is polygenic inheritance?
A trait resulting from multiple genes, each potentially having multiple alleles, with phenotypic outcomes due to the additive effects of these alleles.
What is hemophilia and what causes it?
A sex-linked trait due to the inability to produce clotting factor 8.
How can hemophiliacs lead a near-normal life?
By receiving factor 8 through blood transfusions.
What are the genotypes of the F2 generation from the pink snapdragons?
C_R C_R, C_R C_W, C_W C_W.
What is a heterozygous organism?
An organism with different alleles of a gene present.
How does the phenotypic ratio differ in sex-linked traits?
It differs in male and female progeny of a cross.
How can the environment affect phenotype?
Environmental factors like diet and temperature can influence the expression of traits.
What type of inheritance pattern is observed in colorblindness?
Criss-cross inheritance (mother to son).
What tool is used to visualize genetic crosses in Dihybrid Inheritance?
Punnett square.
In X-linked recessive characteristics, which sex is more commonly affected?
Males are more commonly affected than females.
What are the phenotypes involved in the example provided?
Round, yellow; round, green; wrinkled, yellow.
What is the genetic composition of queen and worker bees compared to drones?
Queens and workers are diploid females, while drones are haploid males.
If a plant is heterozygous, what can it pass to its offspring?
Either the dominant or recessive allele.
What is a key clue to interpreting pedigrees?
Studying the line of descent to deduce gene inheritance.
What gametes are produced by the red and white snapdragons during meiosis?
Red produces all C_R; White produces all C_W.
What is an example of codominance in humans?
AB blood group.
How many different alleles determine the ABO blood group?
3 different alleles.
If a plant is homozygous dominant, what will it pass to its offspring?
The dominant allele (P) to all offspring.
What is the ratio of yellow seeds to green seeds in the F2 generation?
6/16 yellow seeds to 2/16 green seeds.
What is a limitation of studying F1 and F2 generations in humans?
They are too small for statistical analysis.
What is the expected Dihybrid Test Cross ratio when crossing RrYy with rryy?
1 round yellow : 1 round green : 1 wrinkled yellow : 1 wrinkled green.
What are homologous chromosomes?
Chromosomes that are similar but not identical, sharing the same length, size, and position of centromere.
What is the phenotype of the F1 generation when red and white snapdragons are crossed?
Pink.
What is incomplete dominance?
A case where neither allele is completely dominant, resulting in an intermediate phenotype in the F1 offspring.
What is an example of incomplete dominance in plants?
Flower color in Antirrhinum (snapdragon).
What is the gene locus for the ABO blood group represented by?
The letter I (isohaemagglutinin).