Question 1

Meglitinides are similar to ___ in their function.

Accepted Answer

Sulfonylureas

Question 2

An example of a meglitinide is ___ (Prandin).

Accepted Answer

Repaglinide

Question 3

Type I Diabetes is often diagnosed in ___, while Type II Diabetes is more common in ___ adults.

Accepted Answer

children, older

Question 4

Adverse effects of sulfonylureas include ___, which can occur due to higher doses, missing meals, or strenuous exercise.

Accepted Answer

hypoglycemia

Question 5

Severe hypoglycemia can lead to ___, convulsions, and death.

Accepted Answer

loss of consciousness

Question 6

In Type 2 DM, GLP-1 levels may be ___, while GIP levels are typically ___.

Accepted Answer

less, normal

Question 7

___ (Amaryl) is a commonly used sulfonylurea.

Accepted Answer

glimepiride

Question 8

___ (DiaBeta, Micronase) is a common sulfonylurea medication.

Accepted Answer

glyburide

Question 9

___ (Orinase) is a common agent in the sulfonylureas category.

Accepted Answer

tolbutamide

Question 10

___ are a type of insulin sensitizer that works by activating PPAR-gamma.

Accepted Answer

Thiazolidinediones

Question 11

Meglitinides increase ___ secretion from pancreatic beta cells.

Accepted Answer

insulin

Question 12

In Type II Diabetes, the body becomes resistant to ___ or doesn't produce enough of it.

Accepted Answer

insulin

Question 13

Sulfonylureas increase glucose entry into ___ and other peripheral tissues.

Accepted Answer

muscle

Question 14

Sulfonylureas are typically used in the ___ stages of the disease.

Accepted Answer

early

Question 15

Symptoms of hypoglycemia from sulfonylureas may include ___, fatigue, and tachycardia.

Accepted Answer

headache

Question 16

One common sulfonylurea is ___ (Dymelor).

Accepted Answer

acetohexamide

Question 17

Symptoms of hypoglycemia from meglitinides may include ___, fatigue, and tachycardia.

Accepted Answer

headache

Question 18

DPP4 inhibitors work by inhibiting ___, an enzyme that breaks down incretins.

Accepted Answer

dipeptidyl peptidase 4

Question 19

One of the benefits of incretin-based therapies is that they can reduce ___ and promote weight loss.

Accepted Answer

appetite

Question 20

DPP4 inhibitors are administered in ___ form.

Accepted Answer

oral

Question 21

___ inhibit the enzyme that breaks down carbohydrates in the intestine.

Accepted Answer

Alpha-Glucosidase Inhibitors

Question 22

Sulfonylureas increase ___ secretion from pancreatic beta cells.

Accepted Answer

insulin

Question 23

Incretin-based therapies involve hormones such as ___ and ___.

Accepted Answer

GLP-1, GIP

Question 24

The overall effect of sulfonylureas is to lower ___ sugar.

Accepted Answer

blood

Question 25

Meglitinides can be used in combination with other ___.

Accepted Answer

agents

Question 26

Incretins regulate the secretion and effects of ___.

Accepted Answer

insulin

Question 27

___ (Diabinese) is another common sulfonylurea.

Accepted Answer

chlorpropamide

Question 28

Severe hypoglycemia can result in ___, convulsions, and death.

Accepted Answer

loss of consciousness

Question 29

Other adverse effects may include headache, bronchitis, and ___ pain.

Accepted Answer

joint and back

Question 30

___ are a class of medications that also stimulate insulin secretion but have a shorter duration of action compared to sulfonylureas.

Accepted Answer

Meglitinides

Question 31

Type I Diabetes is primarily caused by the ___ of insulin-producing beta cells.

Accepted Answer

destruction

Question 32

Sulfonylureas have an indirect and direct effect of decreasing hepatic ___ production.

Accepted Answer

glucose

Question 33

Incretins decrease glucagon release from pancreatic ___ cells.

Accepted Answer

alpha

Question 34

One effect of GLP-1 is to reduce ___ and help promote weight loss.

Accepted Answer

appetite

Question 35

Sulfonylureas require reasonable ___ cell function.

Accepted Answer

beta

Question 36

Liraglutide is marketed under the name ___ and is a type of GLP-1.

Accepted Answer

Victoza

Question 37

Other adverse effects of sulfonylureas may include headache, dizziness, skin rashes, and ___ abnormalities.

Accepted Answer

hematologic

Question 38

___ (Glucotrol) is a type of sulfonylurea.

Accepted Answer

glipizide

Question 39

___ (Tolinase) is classified as a sulfonylurea.

Accepted Answer

tolazamide

Question 40

___ are therapies that enhance the effects of incretin hormones to improve insulin secretion.

Accepted Answer

Incretin-Based Therapies

Question 41

___ is an injectable medication that helps control blood sugar levels by slowing gastric emptying.

Accepted Answer

Amylin Analog

Question 42

Hypoglycemia is ___ with GLP-1.

Accepted Answer

not

Question 43

The direct effect of sulfonylureas is to ___ insulin release.

Accepted Answer

increase

Question 44

GLP-1 helps improve the size and function of ___ cells.

Accepted Answer

pancreatic beta

Question 45

Meglitinides are considered to be relatively ___ acting.

Accepted Answer

short

Question 46

GLP-1 and GIP are hormones released from the ___ tract after eating.

Accepted Answer

GI

Question 47

Adverse effects of meglitinides include ___, which can occur due to higher doses, missing meals, or strenuous exercise.

Accepted Answer

hypoglycemia

Question 48

Two options for incretin-based therapies are GLP-1 receptor agonists and ___ inhibitors.

Accepted Answer

Dipeptidyl peptidase 4

Question 49

Gastrointestinal adverse effects of meglitinides include ___, nausea, and diarrhea.

Accepted Answer

heartburn

Question 50

___ are agents that stimulate insulin secretion in patients with Type 2 Diabetes.

Accepted Answer

Sulfonylureas

Question 51

___ are medications that improve insulin sensitivity in the body.

Accepted Answer

Insulin Sensitizers

Question 52

___ are used to lower blood sugar levels by binding bile acids in the intestine.

Accepted Answer

Bile Acid Sequestrants

Question 53

Hypoglycemia is ___ with Dipeptidyl Peptidase 4 Inhibitors.

Accepted Answer

mild

Question 54

Incretin-based therapies mimic the effects of ___ produced GLP-1.

Accepted Answer

endogenously

Question 55

Another example of a meglitinide is ___ (Starlix).

Accepted Answer

Nateglinide

Question 56

Individuals with Type I Diabetes require ___ for management.

Accepted Answer

insulin therapy

Question 57

Type II Diabetes can often be managed with ___ and lifestyle changes.

Accepted Answer

diet, exercise

Question 58

Exenatide is also known as ___ and is administered sub-Q.

Accepted Answer

Byetta

Question 59

Gastrointestinal adverse effects of sulfonylureas include ___, nausea, and diarrhea.

Accepted Answer

heartburn

Question 60

Incretin-based therapies primarily involve the use of ___ inhibitors.

Accepted Answer

DPP4

Question 61

Incretin-based therapies help to prolong the effects of ___ and ___.

Accepted Answer

GLP-1, GIP

Question 62

Examples of DPP4 inhibitors include Linagliptin (Tradjenta), Sitagliptin (___), and Saxagliptin (Onglyza).

Accepted Answer

Januvia

Question 63

___ is a class of drugs that decreases hepatic glucose production and increases insulin sensitivity.

Accepted Answer

Biguanides