What characterizes first-order kinetics?
Click to see answer
Rate is directly proportional to the concentration (linear)
Click to see question
What characterizes first-order kinetics?
Rate is directly proportional to the concentration (linear)
What is a key feature of zero-order kinetics?
Rate is independent of the concentration (non-linear).
Which medications are examples of zero-order kinetics?
Warfarin, Alcohol, Aspirin, Theophylline, Tolbutamide, Phenytoin.
What is the largest capsule size?
3 cm (000).
What factors affect sustained release of medications?
Interaction with body fluid, Medium pH, Enzymatic activity.
What type of drugs are absorbed in the stomach?
Non-ionized, non-polar, lipid-soluble drugs.
What characteristics allow drugs to cross the Blood-Brain Barrier?
Unionized and lipophilic properties.
What factors allow drugs to cross the placenta?
Molecular weight < 500, lipophilic, and non-ionized.
What is the effect of volume of distribution?
It is influenced by solubility, protein binding, and molecular weight.
How does obesity affect lipid-soluble drugs?
It increases the volume of distribution.
What is the excretion pathway for drugs with molecular weight > 500?
They will be excreted in the biliary system.
Is there a time needed to switch from ACE inhibitors to ARBs?
No time is needed.
What is the time required to switch from ACE inhibitors to ARNI?
36 hours.
Where are T-lymphocytes found?
Intercellular spaces.
Where are B-lymphocytes found?
Extracellular spaces.
