What type of drugs are absorbed in the stomach?
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Non-ionized, non-polar, lipid-soluble drugs.
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What type of drugs are absorbed in the stomach?
Non-ionized, non-polar, lipid-soluble drugs.
Is there a time needed to switch from ACE inhibitors to ARBs?
No time is needed.
Where are B-lymphocytes found?
Extracellular spaces.
What factors affect sustained release of medications?
Interaction with body fluid, Medium pH, Enzymatic activity.
How does obesity affect lipid-soluble drugs?
It increases the volume of distribution.
What is the largest capsule size?
3 cm (000).
Where are T-lymphocytes found?
Intercellular spaces.
What characterizes first-order kinetics?
Rate is directly proportional to the concentration (linear)
What characteristics allow drugs to cross the Blood-Brain Barrier?
Unionized and lipophilic properties.
What is the effect of volume of distribution?
It is influenced by solubility, protein binding, and molecular weight.
What is the time required to switch from ACE inhibitors to ARNI?
36 hours.
What is a key feature of zero-order kinetics?
Rate is independent of the concentration (non-linear).
What is the excretion pathway for drugs with molecular weight > 500?
They will be excreted in the biliary system.
Which medications are examples of zero-order kinetics?
Warfarin, Alcohol, Aspirin, Theophylline, Tolbutamide, Phenytoin.
What factors allow drugs to cross the placenta?
Molecular weight < 500, lipophilic, and non-ionized.