A common symptom of respiratory acidosis is ___, which can lead to drowsiness and dizziness.
Click to see answer
headache
Click to see question
A common symptom of respiratory acidosis is ___, which can lead to drowsiness and dizziness.
headache
In respiratory acidosis, the pH of the lungs is ___ while PCO2 is increasing.
decreasing
Nursing management for respiratory acidosis includes monitoring the client's ___ signs.
vital
For severe respiratory acidosis, ___ may be necessary to assist with breathing.
mechanical ventilation
To address respiratory alkalosis, the primary goal is to slow the ___ rate.
breathing
If anxiety is causing respiratory alkalosis, patients may need to be encouraged to ___ their breathing.
slow
In cases of pain-induced rapid breathing, providing ___ can help alleviate the issue.
pain relief
Breathing into a paper bag helps patients with respiratory alkalosis by allowing them to rebreathe ___, which raises its level in the blood.
CO2
To treat metabolic acidosis, it is important to correct the ___ cause.
underlying
For a diabetic patient with metabolic acidosis, it is crucial to control blood ___ and ___ levels.
glucose, insulin
If metabolic acidosis is mild, administering ___ fluid may be sufficient.
I.V.
In cases of severe metabolic acidosis, ___ bicarbonate may be given.
I.V.
Metabolic alkalosis often results from an electrolyte ___ that needs to be corrected.
imbalance
To correct metabolic alkalosis, it is important to replace fluid, ___, and potassium.
sodium
Type 1 respiratory failure is characterized by ___ (PaO2 < 8 kPa) and ___ (PaCO2 < 6.0 kPa).
hypoxaemia, normocapnia
A decrease in WBC can be caused by ___, bone marrow failure, or autoimmune disease.
Drug toxicity
Coumarin-type drugs, such as ___, cause a decrease in the production of prothrombin and other factors.
Warfarin
The change in the PT takes several days to reach the desired ___.
INR
Serious bleeding or immediate reversal of anticoagulation may be treated with ___ concentrated clotting factors or FFP.
IV
Alanine transaminase (___) is a cytosol enzyme specific to the liver.
ALT
Aspartate transaminase (___) is a mitochondrial enzyme present in heart, muscle, kidney, and brain.
AST
ALT and AST are present in hepatocytes and leak into blood with ___ cell damage.
liver
Serological screening tests establish whether liver ___, infection, or obstruction is present.
inflammation
The reference range for ALT is ___ unit/L.
4 – 36
The reference range for AST is ___ unit/L.
10 – 40
The reference range for ALP is ___ units/L.
30 – 120
Total protein reference range is ___ g/dL.
6.4 – 8.3
The reference range for Albumin is ___ g/L.
35 – 50
Globulin reference range is ___ g/L.
23 – 34
Total bilirubin reference range is ___ μmol/L.
1.71 – 20.5
The reference range for Direct bilirubin is ___ µmol/L.
< 5.1
Indirect bilirubin reference range is ___ μmol/L.
3.4 – 12.0
Alkaline phosphatase (ALP) is primarily found in the tissues of the ___, bone, intestine, kidneys, and placenta.
liver
Haemolytic anemia is associated with increased levels of ___ bilirubin.
unconjugated (indirect)
Extensive liver metastasis can lead to increased levels of ___ bilirubin.
conjugated (direct)
Gallstones are a common disorder that can cause increased levels of ___ bilirubin.
conjugated (direct)
Cirrhosis is associated with increased levels of ___ bilirubin.
unconjugated (indirect)
Renal function tests are used to evaluate the severity of ___ disease.
kidney
Renal function tests assess the client's ___ function.
kidney
Common tests of renal function include serum creatinine and ___ clearance.
creatinine
Blood urea nitrogen is a common test of renal function along with serum creatinine and ___ clearance.
creatinine
The reference range for creatinine (Cr) in males is ___ to ___ µmol/L.
53, 106
The reference range for blood urea nitrogen (BUN) is ___ to ___ mmol/L.
3.6, 7.1
The creatinine clearance (CrCl) for females is ___ to ___ ml/min.
87, 107
The estimated glomerular filtration rate (eGFR) should be greater than ___ ml/min/1.73 m².
60
Creatinine (Cr) is a catabolic product of ___ phosphate.
creatine
Creatinine is excreted entirely by the ___.
kidneys
An elevation in Cr suggests ___ of the disease process.
chronicity
A doubling of Cr suggests a ___% reduction in GFR.
50
The Cr level is interpreted in conjunction with the ___ test.
BUN
Abnormal elevation in creatinine may indicate renal disorders such as ___ or acute tubular necrosis.
glomerulonephritis
Slight increases in creatinine level can occur after meals, especially after ingestion of large quantities of ___.
meat
Blood urea nitrogen (BUN) measures the amount of ___ in the blood.
urea nitrogen
Urea is formed in the liver as the end product of ___ metabolism.
protein
BUN is directly related to the metabolic function of the liver and the excretory function of the ___.
kidney
Elevated BUN levels indicate a condition known as ___.
azotemia
Nearly all renal diseases cause inadequate excretion of urea, leading to a rise in blood urea concentration above ___.
normal
BUN is interpreted in conjunction with the ___ test.
Cr
Increased levels of renal function tests can be caused by ___ causes, ___ causes, and ___ causes.
prerenal, renal, postrenal
One prerenal cause of increased renal function test levels is ___ .
Hypovolemia
A renal cause of increased renal function test levels is ___ .
Renal diseases
The CrCl test requires a ___-hour urine collection and serum Cr level.
24
The 24-hour urine collection is considered too ___ and expensive for routine clinical use.
time-consuming
GFR can be estimated (eGFR) using serum Cr, age, and numbers that vary depending on ___ and ___.
sex and ethnicity
Increased levels of CrCl can be caused by ___ and ___.
exercise, pregnancy
Decreased levels of CrCl may indicate ___ kidney function, such as renal artery atherosclerosis or glomerulonephritis.
impaired
Conditions causing decreased GFR include congestive heart failure and ___ with ascites.
cirrhosis
High cardiac output syndromes, such as ___, can lead to increased levels of CrCl.
sepsis
Electrolytes assist with the regulation of ___ balance.
water
Electrolytes are essential for ___ activity.
neuromuscular
One of the functions of electrolytes is to regulate and maintain ___ balance.
acid-base
Common electrolytes include Na+, Cl-, and ___.
Mg2+
___ is listed as a common electrolyte along with Potassium, Phosphates, and Proteins.
Ca2+
A common symptom of hypokalemia includes ___ and vomiting.
nausea
In hypokalemia, the ECG may show ___ T waves.
flattened
Hypokalemia can result in ___ as a sign of low blood pressure.
↓BP
Muscle weakness in hypokalemia can be associated with ___ cramps.
leg
Headache can be a symptom of ___ .
Hyponatremia
Anorexia can be a sign of ___ .
Hyponatremia
Calcium (Ca2+) is essential for ___ nerve impulse transmission.
transmitting
Calcium helps regulate ___ contraction and relaxation, including cardiac muscle.
muscle
Calcium is instrumental in activating enzymes that stimulate many essential ___ reactions in the body.
chemical
Calcium plays a role in ___ coagulation.
blood
Hypoparathyroidism is a condition that can lead to ___ .
hypocalcemia
One of the symptoms of hypocalcemia is ___ .
numbness
Prolonged ___ interval is an ECG finding in hypocalcemia.
QT
Massive transfusion of citrated blood can lead to ___ .
hypocalcemia
Generalized peritonitis can cause ___ .
hypocalcemia
Diuretic phase of kidney injury may result in ___ .
hypocalcemia
Bronchospasm can be a sign of ___ .
hypocalcemia
Phosphorous is the primary anion of the ___.
ICF
Phosphorous is essential for the formation of ___ and 2,3-diphosphoglycerate.
adenosine triphosphate (ATP)
Phosphorous helps maintain ___ balance, the nervous system, and intermediary metabolism.
acid-base
Phosphorous provides structural support to ___ and ___.
bones, teeth
Hyperphosphatemia can be caused by ___ kidney injury and chronic kidney disease.
acute
One of the signs of hyperphosphatemia is ___, which is characterized by muscle spasms.
tetany
Excessive intake of phosphorus and ___ can lead to hyperphosphatemia.
vitamin D
A symptom of hyperphosphatemia includes ___ and vomiting.
nausea
In hyperphosphatemia, muscle weakness can occur due to ___ levels of calcium.
low
Soft tissue calcifications in the lungs, heart, kidneys, and cornea can be a sign of ___ .
hyperphosphatemia
Signs and symptoms of hypophosphatemia include ___ and ___.
Paresthesia, Muscle weakness
One cause of hypophosphatemia is ___ withdrawal.
Alcohol
Refeeding syndrome after starvation consumes ___ .
PO43-
A symptom of hypophosphatemia can be ___ pain and tenderness.
Bone
Hypophosphatemia can lead to ___ failure.
Respiratory
Diabetic ketoacidosis is a condition that can cause ___ .
Hypophosphatemia
Signs of hypophosphatemia may include ___ and confusion.
Seizures
Malabsorption can lead to ___ .
Hypophosphatemia
Hyperparathyroidism is associated with ___ .
Hypophosphatemia
A sign of hypophosphatemia is ___ .
Nystagmus
When interpreting serum electrolyte reports, it is important to note that the laboratory report reflects only ___ levels.
serum
The level of electrolytes in the serum is very close to electrolytes in the ___ fluid.
interstitial
Radiology uses ___ technology to diagnose and treat disease.
imaging
Diagnostic radiology allows us to see ___ inside your body.
structures
Using imaging, a radiologist can diagnose the cause of your ___ .
symptoms
Radiology can monitor how well your body is responding to a ___.
treatment
One of the illnesses that can be screened for using radiology is ___ cancer.
breast
Radiology can also screen for ___ disease.
heart
X-rays are a form of electromagnetic radiation that can ___ the human body.
penetrate
X-rays are absorbed by materials in differing amounts based on their ___ and ___.
density, composition
Bone absorbs X-rays well due to its ___ density.
high
Soft tissue has a ___ density, thus absorbs fewer X-rays.
lower
A ___ image is produced from X-ray imaging.
2D
To determine the projection of a chest X-ray, check the position of the ___ and ___.
scapulae, clavicles
If the scapulae overlie the lung field, the film is ___ projection.
anteroposterior (AP)
If the scapulae do not overlie the lung field, the film is ___ projection.
posteroanterior (PA)
When checking orientation on a chest x-ray, do not assume the heart is always on the ___.
left
To identify rotation in a chest x-ray, the medial ends of the clavicles should be equidistant from the ___ process.
spinous
If one clavicle is nearer than the other on a chest x-ray, the patient is ___.
rotated
In assessing a chest x-ray, the medial ends of the clavicles should be aligned with the ___ of the vertebral column.
spinous processes
In a chest X-ray, the vertebral bodies should only be visible through the ___ shadow at the lower part of the cardia.
cardiac
The degree of inspiration is determined by counting the number of ribs ___ the diagram.
above
The midpoint of the right hemidiaphragm should be between the ___ and ___ ribs anteriorly.
5th, 7th
The cardiothoracic ratio (CTR) should be between ___ and ___.
0.42, 0.50
The maximum diameter of the heart is less than half of the ___ diameter.
transthoracic
Any abnormally dense areas of the transthoracic shadow may indicate ___ issues.
cardiac
The most common cause of gas under the diaphragm is ___ perforation.
hollow viscous
The chest X-ray shows the lungs appearing mostly clear with some possible ___ in the lower regions.
opacities
The X-ray indicates that the mediastinum appears normal in ___.
width
A possible ___ tube is visible running down the esophagus in the chest X-ray.
nasogastric
The ECG cable is shown coming from the patient's right shoulder across the chest and is highlighted in ___.
blue
The findings on the X-ray indicate that the penetration is ___.
OK
The X-ray identifies a foreign body, including an ET tube about the ___.
carina
The X-ray is labeled as ___ on the right side of the chest.
PORTABLE
The X-ray is taken in the ___ view.
AP
The right internal jugular central line is noted as a foreign body in the chest X-ray along with the ___ cable.
ECG
A CT scan is a ___, noninvasive x-ray procedure.
painless
CT scans have a unique capability of distinguishing minor differences in the ___ of tissue.
density
During a CT scan examination, the detectors are both ___ around the body.
rotating
CT scans can acquire ___ images.
multiple
A CT scan provides a ___ image of an organ or structure.
3D
MRI uses powerful magnets and ___ waves to create pictures of the body.
radio
MRI is considered ___ because it does not use radiation.
noninvasive
MRI provides better contrast between normal and abnormal tissue than ___ scan.
CT
Angiograms can be used to assess the arteries of the ___, heart, lung, kidneys, or lower extremities.
brain
An EEG is a test used to measure the ___ activity of the brain.
electrical
EEG is useful in diagnosing ___ disorders.
seizure
One of the conditions evaluated by EEG is ___ syndrome.
organic brain
EEG can help in the determination of ___ death.
brain
During normal sleep, brainwaves are relatively ___ and have a lower amplitude.
smoother
Brainwaves during an absence seizure are characterized by ___ spikes and increased amplitude.
sharp
The brain activity during an absence seizure is described as ___ compared to normal sleep.
disturbed
To determine respiratory status, one must assess pH, PaCO₂, and ___.
PaO₂
The kidneys can regulate the pH by excreting ___ and controlling serum bicarbonate through reabsorption.
H+
It takes the kidneys ___ days to restore the pH to normal.
Several
To determine metabolic acid-base balance, one must assess pH, PaCO2, HCO3, and ___.
BE
In metabolic alkalosis, the pH is ___ and HCO3- is ___.
alkalotic, alkalotic
In metabolic acidosis, the pH is ___ and HCO3- is ___.
acidotic, acidotic
An example of metabolic alkalosis is when the pH is ___ and HCO3- is ___.
7.5, 32 mmol/L
An example of metabolic acidosis is when the pH is ___ and HCO3- is ___.
7.32, 19 mmol/L
A negative base excess (BE) indicates ___ acidosis.
metabolic
A positive base excess (BE) indicates ___ alkalosis.
metabolic
Base excess (BE) reflects the number of ___ available in the blood to help buffer changes in pH.
anions
If the pH value is less than ___, it indicates acidosis.
7.35
If the pH value is greater than ___, it indicates alkalosis.
7.45
In primary respiratory causes, pH and PCO2 move in ___ directions.
opposite
In primary metabolic causes, pH and HCO3- move in ___ direction.
same
One type of acid-base imbalance is ___ acidosis.
Respiratory
One type of acid-base imbalance is ___ alkalosis.
Respiratory
One type of acid-base imbalance is ___ acidosis.
Metabolic
One type of acid-base imbalance is ___ alkalosis.
Metabolic
Respiratory acidosis is characterized by the accumulation of ___ in the body.
CO2
The accumulation of CO2 leads to the production of ___ acid.
carbonic
Clinical manifestations of respiratory acidosis include ___ respiration, decreased BP, and skin/mucosa that is pale to cyanotic.
Rapid, Shallow
Lung compensation occurs for ___ causes.
metabolic
To treat respiratory acidosis, it is important to improve ___.
ventilation
In cases of respiratory acidosis, administering ___ can help improve breathing.
bronchodilators
The reference value for Lymphocytes is ___ x 10^9/L.
0.9 - 3.4
The reference value for Platelets in adults is ___ x 10^9/L.
150 - 420
An increase in Hb may indicate ___, congenital heart disease, or severe dehydration.
Erythrocytosis
A decreased level of aPTT may occur in the early stage of ___.
DIC
Extensive cancer can lead to a ___ level of aPTT.
decreased
An aPTT greater than ___ seconds indicates that too much heparin is being given.
100
The effect of heparin can be reversed by ___ sulfate.
protamine
Heparin's effect is immediate and ___ lived, unlike that of warfarin.
short
Heparin prevents intravascular clotting during ___ of the vessels.
clamping
If the PT is greatly prolonged, evaluate the patient for ___ tendencies.
bleeding
Common disorders for prolonged PT include ___ disease.
liver
A common disorder for prolonged PT is ___ biliary disease.
obstructive
Hereditary factor deficiency can include Factors ___, ___, ___ or ___.
II, V, VII, X
A deficiency in ___ can lead to prolonged PT.
Vitamin K
___ is a condition that can cause prolonged PT.
DIC
Massive ___ transfusion can result in prolonged PT.
blood
Decreased muscle mass will result in ___ CrCl values.
lower
If more CO₂ is retained, it leads to more carbonic acid and shifts toward ___.
acidosis
Hyperventilation results in less carbonic acid and shifts toward ___.
alkalosis
The lungs can shift the pH of the blood within a few ___.
minutes
Upon completion of the lecture, students will be able to analyse the value of laboratory data including ___, CBC, Coagulation test, Liver function test, Renal function test, and common measured electrolytes.
ABG
Students will understand the basic principle of interpretation of ___ X-ray.
chest
Students will describe the basic principle of common ___ tests.
diagnostic
Judging the value of laboratory data requires assessing the ___ of the test and the contextual ___.
credibility, relevance
A sudden change in laboratory values is of greatest concern when there is a ___ in the patient's condition.
deterioration
Clients may exhibit more symptoms with an abruptly changed result compared to those with a ___ change in data due to the body's adaptation.
chronic
When judging the value of laboratory results, one must consider the ___ that may affect the results.
factors
Clients with abnormal laboratory results may exhibit a ___ of symptoms that can provide insight into their condition.
pattern
Other assessment data that suggest a changed laboratory result may include ___ and ___ findings.
clinical, historical
Factors that may change patterns in laboratory results include ___, ___, and ___ changes.
medication, lifestyle, environmental
Blood gas analysis is used to evaluate ___ function.
respiratory
Blood gas analysis provides a measure to determine - balance.
acid-base
The integration of respiratory, renal, and cardiovascular system functions is essential to maintain normal - balance.
acid-base
Different types of blood gases include Arterial blood gases (ABG), venous blood gases (VBG), capillary blood gases, and ___ blood gases.
cord
Abnormal blood gas findings can indicate a ___ or ___ disorder.
respiratory, metabolic
A postrenal cause of increased renal function test levels is ___ .
Ureteral obstruction
___ is a prerenal cause that can lead to increased renal function test levels.
Shock
___ is a prerenal cause associated with increased renal function test levels due to fluid loss.
Burns
___ is a prerenal cause that can lead to increased renal function test levels due to insufficient blood volume.
Dehydration
___ is a prerenal cause that can lead to increased renal function test levels due to heart issues.
Congestive heart failure
___ is a prerenal cause that can lead to increased renal function test levels due to infection.
Sepsis
___ is a renal cause that can lead to increased renal function test levels due to medication effects.
Nephrotoxic drugs
___ is a postrenal cause that can lead to increased renal function test levels due to blockage in the urinary tract.
Bladder outlet obstruction
CrCl is a measure of the ___ of the kidney.
glomerular filtration rate (GFR)
The ability of the nephron to act as a filter affects the ___ of CrCl.
amount of blood available to be filtered
When one kidney becomes diseased, the other kidney can compensate by increasing its ___ rate.
filtration
Angiograms are indicated for the diagnosis of ___, stenosis, emboli, thrombosis, aneurysms, tumors, congenital malformation, or trauma.
occlusions
Monitoring the client's ___ is essential to assess the impact of metabolic acidosis on their health.
vital signs
Excessive acid loss in metabolic alkalosis can occur due to ___ vomiting.
repeated
In metabolic alkalosis, bicarbonate retention leads to an increase in ___ levels.
base
Clinical manifestations of metabolic alkalosis include ___, lethargy, and confusion.
restlessness
A common symptom of metabolic alkalosis is ___, which can lead to muscle cramps and tingling of fingers and toes.
hypokalemia
In metabolic alkalosis, the pH level is typically ___, indicating alkalosis.
increased
Nursing management for metabolic alkalosis includes monitoring the client's ___ signs.
vital
It is important to monitor the client's ___ status in cases of metabolic alkalosis.
neurological
Monitoring the client's ___ intake and output is crucial in managing metabolic alkalosis.
fluid
In metabolic alkalosis, the heart rate may be affected, leading to potential ___.
dysrhythmias
Nursing management for metabolic alkalosis includes assessing motor function and sensation in the ___ .
extremities
Laboratory results should be monitored and reported ___ in cases of metabolic alkalosis.
timely
Administering medications and intravenous fluid as prescribed is part of the nursing management for ___ .
metabolic alkalosis
An increase in pH indicates a condition that is ___ and can be caused by disorders such as alkali ingestion and vomiting.
Alkalotic
A decrease in pH indicates a condition that is ___ and is associated with disorders like asthma and cardiac disease.
Acidotic
An increase in PCO2 can be seen in conditions such as late-stage asthma and ___ disorders.
respiratory
A decrease in PCO2 may occur in early-stage asthma and ___ due to hyperventilation.
dysrhythmias
An increase in PO2 is often a result of ___ and hyperbaric oxygen exposure.
hyperventilation
A decrease in PO2 can be associated with acute respiratory distress syndrome (ARDS) and ___ disorders.
cardiac
In cases of metabolic acidosis, the primary problem is a ___ in HCO3.
decrease
For metabolic acidosis, the compensation observed is a ___ in PaCO2.
decrease
In metabolic alkalosis, the primary problem is an ___ in HCO3.
increase
For metabolic alkalosis, the compensation observed is an ___ in PaCO2.
increase
In respiratory acidosis, the primary problem is an ___ in PaCO2.
increase
For respiratory acidosis, the compensation observed is an ___ in [HCO3].
increase
In respiratory alkalosis, the primary problem is a ___ in PaCO2.
decrease
For respiratory alkalosis, the compensation observed is a ___ in [HCO3].
decrease
Renal compensation occurs for ___ causes.
respiratory
The Arterial Blood Gas (ABG) test assesses the ability of the lung to provide adequate ___ and remove ___, which reflects ventilation.
oxygen, carbon dioxide
The ABG test evaluates the ability of the kidneys to absorb or excrete ___ ions to maintain normal body ___.
bicarbonate, pH
The purpose of arterial blood gas analysis includes assessing ___ balance.
acid-base
Arterial blood gases are used to evaluate the ___ status.
oxygenation
One of the purposes of arterial blood gas analysis is to identify abnormalities of ___.
ventilation
Venous Blood Gas (VBG) provides data on ___ delivery and ___ consumption.
oxygen, oxygen
VBG reflects the balance between the amount of oxygen used by tissues and organs and the amount of oxygen returning to the ___ side of the heart in the blood.
right
VBG is recommended to guide goal-directed therapy in postoperative patients at risk for ___ instability.
haemodynamic
Using VBG may decrease ___ and ___ in patients with septic shock.
morbidity, mortality
VBG can help identify ___ hypoxia in patients.
tissue
The pH in blood gas analysis measures the concentration of ___ ion.
hydrogen
PaCO2 represents the partial pressure of ___ in the blood.
carbon dioxide
PaO2 indicates the partial pressure of ___ in the blood.
oxygen
HCO3 is a ___ value in blood gas analysis.
calculated
Base excess (BE) measures the amount of acid/base needed to titrate plasma pH back to ___.
7.4
HCO3 is the main buffer in ___ fluid.
extracellular
Base excess reflects the metabolic capacity of bases such as HCO3 and ___ in blood gas analysis.
PO4
The actual HCO3 value is affected by ___ and respiratory conditions.
metabolic
Base excess indicates the net excess or deficit of ___.
HCO3
The normal pH range for arterial blood is ___ to ___.
7.35, 7.45
The PCO2 level in arterial blood should be between ___ and ___ kPa.
4.6, 6.0
The normal PO2 range for venous blood is ___ to ___ kPa.
2.7, 6.5
HCO3- levels in arterial blood typically range from ___ to ___ mmol/L.
22, 26
The base excess (BE) in arterial blood is typically between ___ to ___ mmol/L.
-2, +2
O2 saturation in arterial blood should be between ___% and ___%.
95, 99
Every organ system relies on ___ balance.
pH
The two main modulators of pH balance are the ___ system and ___ system.
pulmonary, renal
The pulmonary system adjusts pH by ___ dioxide.
carbon
The renal system affects pH by reabsorbing ___ and excreting acids.
bicarbonate
The main buffer system in the body is the ___ – ___ acid system.
Bicarbonate, carbonic
The reaction involving carbonic acid and bicarbonate is represented as ___ + ___ ↔ H₂CO₃ ↔ H⁺ + HCO₃⁻.
CO₂, H₂O
The enzyme that facilitates the acid-base balance mechanism is ___ anhydrase.
Carbonic
The level of PaCO₂ is primarily controlled by the ___.
lungs
During exhalation, carbon dioxide is exhaled into the ___.
environment
Signs of respiratory distress to observe include restlessness, anxiety, confusion, and ___.
tachycardia
To assist a patient with ventilation in respiratory acidosis, it is important to elevate the head of the bed in ___ position if no contraindication.
high Flower's
In respiratory acidosis, the patient may experience muscle weakness and ___.
hyperreflexia
In respiratory acidosis, the HCO3 level is typically indicated as ___.
N
In respiratory alkalosis, excessive ___ is blown off due to hyperventilation.
CO2
A clinical manifestation of respiratory alkalosis includes ___ of extremities.
numbness and tingling
In respiratory alkalosis, the rate and depth of breathing are ___ (increased/decreased).
increased
One of the nursing management strategies for respiratory alkalosis is to encourage the client to breathe ___.
slowly
In respiratory alkalosis, the PaCO2 level is typically ___ (increased/decreased).
decreased
A common symptom of respiratory alkalosis is ___, which can lead to muscle cramping and seizures.
anxiety
The pH level in respiratory alkalosis is typically ___ (normal/increased).
increased
Nursing management for respiratory alkalosis includes monitoring the client's ___ signs.
vital
In respiratory alkalosis, the HCO3 level is typically ___ (normal/increased).
normal
A patient with respiratory alkalosis may experience ___ due to hyperventilation.
tachycardia
Tissue hypoperfusion produces ___ acid in metabolic acidosis.
lactic
Common clinical manifestation of metabolic acidosis includes ___ and ___ near the stomach.
Nausea, Vomiting
In severe acidosis, the body may exhibit ___ respirations as a compensatory mechanism.
Kussmaul
Monitoring the client's ___ status is crucial in managing metabolic acidosis.
neurological
In metabolic acidosis, the pH level is expected to be ___ according to ABG values.
decreased
The nursing management for metabolic acidosis includes monitoring the client's ___ and output.
fluid intake
Deep and laborious respiratory compensation is a response to ___ in metabolic acidosis.
acidosis
In metabolic acidosis, the HCO3 level is expected to show a ___ trend.
decrease
The presence of ___ is common in diabetic ketoacidosis (DKA), leading to metabolic acidosis.
hyperglycemia
Activated partial thromboplastin time (aPTT) is a more sensitive version of the PTT and is used to monitor the patient's response to ___ therapy.
heparin
The International Normalized Ratio (___) is the patient's prothrombin time (PT) ratio and the normal mean PT time raised to the power of the international sensitivity index.
INR
The INR is a measure of the sensitivity of the specific tissue factor used in the test, as compared with a ___ standard.
World Health Organization
INR is the preferred reporting to monitor patients on ___ antagonist therapy.
vitamin K
The reference value for aPTT is ___ seconds.
28.2 - 37.4
The reference value for PT is ___ seconds.
9.5 - 12
The reference value for INR is ___ to ___.
0.8 - 1.1
Increased levels of aPTT can indicate ___ factor deficiencies, such as von Willebrand disease.
congenital clotting
Cirrhosis of the liver can lead to an ___ level of aPTT.
increased
Vitamin K deficiency is associated with an ___ level of aPTT.
increased
Heparin administration can result in ___ levels of aPTT.
increased
Type 1 respiratory failure occurs due to ___ mismatch, where the volume of air flowing in and out of the lungs is not matched with the flow of blood to the lung tissue.
ventilation/perfusion (V/Q)
In Type 1 respiratory failure, the rise in PaCO2 triggers an increase in a patient's overall ___ ventilation.
alveolar
Type 2 respiratory failure is characterized by ___ (PaO2 < 8 kPa) and ___ (PaCO2 > 6.0 kPa).
hypoxaemia, hypercapnia
Type 2 respiratory failure occurs due to ___ hypoventilation, which affects oxygenation and CO2 elimination.
alveolar
Increased resistance from airway obstruction, such as ___, can lead to hypoventilation in Type 2 respiratory failure.
COPD
Reduced compliance of lung tissue can be caused by conditions like ___ or rib fractures.
pneumonia
A condition that can reduce the strength of respiratory muscles, contributing to Type 2 respiratory failure, is ___ disease.
motor neuron
Drugs that act on the respiratory center, such as ___, can reduce overall ventilation and lead to Type 2 respiratory failure.
opiates
Haematology is the study of ___ and ___ in health and in disease.
blood, blood-forming organs
The most common tests used in haematology are the complete blood count (CBC), the ___, and ___ profile.
peripheral blood smear, clotting
The WBC test in a CBC is used to help diagnose ___, certain cancers of the blood, and inflammatory diseases.
infection
The RBC test in a CBC is used to watch for ___ and infection.
blood loss
The platelet count in a CBC is used to diagnose or to watch certain types of ___ and clotting disorders.
bleeding
The PT test in a clotting profile is used to evaluate ___ and clotting disorders.
bleeding
The PTT test in a clotting profile is used to watch ___ therapies.
anticoagulation
The INR is used in conjunction with PT and PTT to monitor ___ therapies.
anticoagulation
The CBC identifies the total number of blood ___, WBC and Platelets (Plt), Haemoglobin (Hb), and Haematocrit (Hct).
RBC
RBCs are filled with ___, which has a strong affinity for oxygen.
Hb
The composition of blood includes ___% plasma, ___% white blood cells and platelets, and ___% red blood cells.
55, 4, 41
WBC counts involve the numerical reporting of the total number of ___.
WBCs
The WBC differential cell count describes and classifies the white cell components including ___, lymphocytes, monocytes, eosinophils, and basophils.
neutrophil
Eosinophils are associated with ___ mechanisms.
allergic and parasitic response
Basophils contain ___ and ___.
histamine, heparin
Monocytes are primarily involved in ___.
phagocytosis
Lymphocytes are responsible for the secretion of ___.
antibodies
The reference value for Hemoglobin (Hb) in males is ___ g/dL.
14.0 - 18.0
The reference value for Hemoglobin (Hb) in females is ___ g/dL.
11.5 - 15.5
The reference value for White Blood Cells (WBC) in adults is ___ x 10^9/L.
4.3 - 10.3
The reference value for Neutrophils is ___ x 10^9/L.
1.6 - 7.5
The reference value for Eosinophils is ___ x 10^9/L.
0.0 - 0.6
The reference value for Basophils is ___ x 10^9/L.
0.0 - 0.3
The reference value for Monocytes is ___ x 10^9/L.
0.0 - 1.2
An increase in Platelet count may be associated with ___ tumors or a temporary increase after splenectomy.
Malignant
Possible disorders associated with a decrease in Hb include anemia, cirrhosis, and ___ disease.
Renal
Increased WBC count can be a sign of ___, leukemic neoplasia, or trauma.
Infection
A decrease in Platelet count can occur after viral infections, AIDS, or ___ disorders.
haemolytic
Severe dehydration can lead to an increase in ___ levels.
Hb
Bone marrow failure may result in a decrease in both ___ and WBC counts.
Hb
Trauma can cause an increase in ___ count.
WBC
Taking heparin may lead to a decrease in ___ count.
Platelet
An increase in neutrophils may indicate a ___ infection or ___.
bacterial, trauma
A decrease in neutrophils can be associated with ___ diseases such as Hepatitis or ___.
viral, Influenza
An increase in basophils is often linked to ___.
Leukaemia
A decrease in basophils may result from ___ therapy or an ___ reaction.
corticosteroid, allergic
Eosinophils increase in response to ___ reactions or ___ infestations.
allergic, parasitic
A decrease in eosinophils can be caused by ___ therapy.
corticosteroid
An increase in lymphocytes is commonly seen in ___ infections or chronic ___ infections.
viral, bacterial
A decrease in lymphocytes can be indicative of ___ infection, particularly affecting the CD4 count.
HIV
Monocytes may increase due to chronic ___ disease or ___.
inflammatory, Malaria
A decrease in monocytes can occur due to injuries or infections such as ___ virus.
Epstein-Barr
Coagulation tests are used to determine why a patient is ___, ___, or forming clots abnormally.
bleeding, bruising
Prothrombin time (PT) measures the clotting ability of factors ___, ___, ___, ___, and ___.
I (fibrinogen), II (prothrombin), V, VII, X
Partial thromboplastin time (PPT) is a nonspecific test that demonstrates a lack of any of the various clotting factors except factor ___.
VII
One cause of hypercalcemia is ___ disease.
Hyperparathyroidism
A symptom of hypercalcemia includes ___ weakness.
Muscular
Prolonged immobilization can lead to ___ levels of calcium in the blood.
high
Overuse of calcium supplements can result in ___.
hypercalcemia
A symptom of hypercalcemia is ___ and vomiting.
nausea
In hypercalcemia, patients may experience ___ deep tendon reflexes.
hypoactive
Lethargy is a sign of ___ levels of calcium in the blood.
high
Deep bone pain can be a symptom of ___ disease.
malignant neoplastic
ECG changes in hypercalcemia may include a shortened ST segment and ___ interval.
QT
Bradycardia and heart block can occur in patients with ___ levels of calcium.
high
Hypocalcemia can be caused by ___ deficiency.
Vitamin D
A sign of hypocalcemia includes ___ of fingers, toes, and circumoral region.
tingling
A positive ___ sign is associated with hypocalcemia.
Trousseau
The highest concentrations of alkaline phosphatase (ALP) are found in the liver, biliary tract epithelium, and ___.
bone
Extra- and intrahepatic cholestasis can occur with or without raised ___.
bilirubin
The highest levels of alkaline phosphatase (ALP) result from primary biliary cirrhosis and hepatic ___.
metastases
Total protein in liver function tests measures ___ and ___.
albumin, globulin
Albumin helps maintain ___ osmotic pressure.
colloidal
Globulin is classified into ___, ___, and ___.
alpha, beta, gamma
One of the functions of albumin is to transport important blood constituents such as ___, ___, and ___.
drugs, hormones, enzymes
Globulin helps fight ___ and move nutrients throughout the body.
infection
Total protein is an important measure of ___.
nutrition
A low total protein level may indicate ___ disease.
Liver
Malnutrition can lead to ___ total protein levels.
low
High total protein levels may be associated with ___ myeloma.
Multiple
Celiac disease is an example of a condition that can cause ___ total protein levels.
low
An infection such as ___ can result in high total protein levels.
HIV
___ disease is a potential cause of low total protein levels due to malabsorption.
Crohn's
There are ___ forms of bilirubin: prehepatic bilirubin and conjugated bilirubin.
2
Prehepatic bilirubin is also known as ___ bilirubin.
unconjugated/indirect
Bilirubin metabolism starts with the breakdown of ___ in the reticuloendothelial system.
RBCs
Hemoglobin is released from RBCs and broken down into ___ and ___ molecules.
heme, globin
Heme is catabolized to form biliverdin and then transforms into ___ bilirubin.
unconjugated (indirect)
In the liver, indirect bilirubin is conjugated with a ___, resulting in conjugated bilirubin.
glucuronide
Conjugated bilirubin is excreted from the liver cells into the ___ ducts.
bile
After conjugation in the liver, bilirubin is transformed into ___ bilirubin.
conjugated (direct)
Indirect bilirubin travels to the liver where it conjugates with glucuronide to form ___ bilirubin.
direct (conjugated)
The final product of bilirubin metabolism is urobilinogen, which is excreted through ___ and ___.
stool, urine
Increased levels of conjugated (direct) bilirubin can be caused by ___, extrahepatic duct obstruction, and extensive liver metastasis.
Gallstones
Common disorders associated with increased levels of unconjugated (indirect) bilirubin include ___ disease of the newborn and haemolytic jaundice.
Haemolytic
A condition that can lead to increased levels of unconjugated bilirubin is ___-volume blood transfusion.
Large
Increased levels of conjugated bilirubin can result from ___ from drugs.
Cholestasis
One of the causes of increased unconjugated bilirubin is ___; it can also be seen in cases of sepsis.
Hepatitis
Neonatal ___ is a common disorder associated with increased levels of unconjugated bilirubin.
hyperbilirubinemia
Major electrolytes in the intracellular fluid (ICF) are ___ and ___.
potassium (K+), phosphate (PO4^3-)
The body expends a great deal of energy maintaining the high extracellular concentration of ___.
sodium (Na+)
More than 99% of the body calcium (Ca2+) is located in the ___; a small amount of Ca2+ is located outside in the serum.
skeletal system
Laboratories may report phosphorus level as ___ or ___ level.
phosphorus (P), phosphate (PO4^3-)
P is mainly an intracellular ___.
anion
The reference range for potassium is ___ to ___ mmol/L.
3.5 to 5.1 mmol/L
Sodium levels should be between ___ and ___ mmol/L.
135, 145
The normal range for calcium is ___ to ___ mmol/L.
2.20, 2.6
Phosphate reference values range from ___ to ___ mmol/L.
0.8, 1.60
Potassium (K+) is a major ___ within the cell.
cation
Potassium (K+) is important to ___ function.
cardiac
Routine evaluations of potassium levels are important for patients taking ___ or heart medication.
diuretics
Potassium has a profound effect on heart rate and ___.
contractility
Minor changes in potassium concentration can have ___ consequences.
significant
IV potassium is infused at a ___ rate to prevent irritation to the vein.
slow
Serum K+ levels are affected by - balance.
acid-base
In alkalotic states, potassium (K+) levels are ___ .
lower
In acidotic states, potassium (K+) levels are ___.
raised
Hyperkalaemia can be caused by ___ or chronic renal failure.
acute
One of the causes of hyperkalaemia is ___ injury to tissue.
crush
Aldosterone-inhibiting diuretics, such as ___, can lead to hyperkalaemia.
spironolactone
During acidosis, H+ are driven from the blood into the cell, causing K+ to be expelled from the ___.
cell
In dehydration, K+ becomes more ___ in the bloodstream.
concentrated
A common sign of hyperkalaemia is ___ weakness.
muscle
Tachycardia can progress to ___ in hyperkalaemia.
bradycardia
Tall T waves in an ECG indicate possible ___ levels.
potassium
One symptom of hyperkalaemia is ___ paralysis.
flaccid
Anxiety can be a sign of ___ levels in the body.
potassium
ECG changes in hyperkalaemia may include prolonged PR interval and ___ duration.
QRS
Ventricular dysrhythmias and cardiac arrest can occur due to ___ levels of potassium.
elevated
Hypokalemia can be caused by ___, which leads to increased potassium excretion.
renal artery stenosis
One of the signs of hypokalemia is ___, which can lead to muscle weakness.
fatigue
One of the causes of hypokalemia is the administration of ___, which can lead to potassium loss.
diuretics
In hypokalemia, the presence of prominent ___ waves can be observed on an ECG.
U
Hypokalemia can be caused by ___ administration, which affects potassium levels.
insulin
A decrease in renal blood flow due to ascites stimulates the secretion of ___, increasing potassium excretion.
aldosterone
Sodium (Na+) is the major ___ in the extracellular space.
cation
Sodium salts are the major determinants of extracellular ___.
osmolality
An increase in serum Na+ pulls water into the vascular system from the ___ space and the ___.
interstitial, cell
Physiologically, water and sodium are closely ___.
interrelated
An increase in free body water leads to a dilution of serum Na+ and a ___ concentration.
decreased
When free body water decreases, serum Na+ concentration ___.
increases
The kidney compensates for increased serum Na+ concentration by conserving free ___.
water
A rise in serum Na+ level above normal indicates a serious deficit of ___.
water
Hypernatremia can occur due to ___ at high quantities of salt without adequate free water.
ingested
One sign of hypernatremia is ___, which indicates a lack of adequate hydration.
thirst
A symptom of hypernatremia includes a ___ body temperature.
elevated
Hypernatremia may lead to a ___ dry tongue and sticky mucous membranes.
swollen
One of the signs of hypernatremia is ___, which can indicate severe neurological effects.
hallucination
A common symptom of hypernatremia is ___, which can affect the patient's alertness.
lethargy
Restlessness can be a sign of ___ in patients with hypernatremia.
hypernatremia
Tonic-clonic seizures can occur as a severe symptom of ___.
hypernatremia
Nausea and vomiting are symptoms associated with ___.
hypernatremia
Hyponatremia can be caused by ___ diet Na+ intake.
Deficient
A sign of hyponatremia includes ___ skin.
Dry
Diarrhoea and ___ can lead to hyponatremia.
vomiting
Administration of ___ can cause hyponatremia.
Diuretics
Large-volume aspiration of pleural or peritoneal fluid can lead to ___ .
Hyponatremia
Excessive oral water intake is a cause of ___ .
Hyponatremia
Syndrome of Inappropriate Anti-diuretic hormone (SIADH) is associated with ___ .
Hyponatremia
A symptom of hyponatremia is ___ and vomiting.
Nausea
___ is a sign of hyponatremia that indicates a possible neurological issue.
Confusion
Muscle cramps and ___ can occur due to hyponatremia.
weakness
A severe symptom of hyponatremia can be ___.
Seizures
___ is a common symptom of hyponatremia that can affect daily activities.
Lethargy
Dizziness can be a sign of ___ .
Hyponatremia
Soft-tissue structures such as the heart and liver are more likely to be accurately characterized by MRI than other ___ methods.
imaging
Implanted metal devices, like a ___, cannot undergo MRI due to the strong magnetic field.
pacemaker
Transdermal patches containing foil should be ___ before undergoing MRI to prevent injury.
removed
MRI provides ___ images of the body.
3D
Ultrasonograms use high-frequency sound waves to create images of ___ and ___.
internal organs, tissues
The echoes produced during an ultrasonogram are used by the computer to create ___.
sonograms
Contrast medium studies use ___ or ___ materials to improve visibility of internal structures.
dyes, contrast
Contrast materials help to ___, ___, or ___ parts of the body for clearer imaging.
outline, highlight, fill in
Contrast material can be administered by mouth, as an enema, as an injection, or through a ___.
catheter
Images from contrast medium studies can be captured on x-ray film or by a ___.
computer
In a T1 MRI without contrast, the lesion appears ___ compared to the surrounding brain tissue.
darker
After the administration of contrast in a T1 MRI, the lesion appears ___ and more defined.
brighter
The brain scans compare a T1 MRI with and without ___ for detecting lesions.
contrast
The images illustrate a single brain metastasis from ___ cancer.
breast
A ___ dye is injected into the blood vessels during an angiogram.
radiopaque
Fluoroscopy and ___ are used to assess the flow through the vessels in an angiogram.
x-ray