What does the motor homunculus represent?
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It represents the body map of motor control in the brain.
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What does the motor homunculus represent?
It represents the body map of motor control in the brain.
Describe the structure of a pyramidal neuron.
It has a pyramid-shaped cell body with an apical dendrite and several extensively branching basal dendrites.
What technique did Ramon y Cajal use to support the neuron doctrine?
The Golgi stain.
What technique cannot resolve structures less than 200 nm apart?
Light microscopy.
What do presynaptic terminals contain that is crucial for neurotransmission?
Small synaptic vesicles filled with neurotransmitters.
What is unique about pseudounipolar neurons?
They have one process leaving the cell body that gives rise to both peripheral and central branches.
What type of synapses are commonly referred to as chemical synapses?
Regular synapses.
What do loss of function experiments test?
Whether a missing component is necessary for a function.
Who was Camillo Golgi?
A scientist who believed in the reticular theory and discovered the Golgi apparatus.
What does the Golgi stain allow scientists to visualize?
The entire morphology of individualized neurons.
How is the Golgi stain applied to neural tissue?
By soaking it in a solution of silver nitrate and potassium dichromate in the dark for several weeks.
What happens when the Golgi stain is applied to nerve cells?
Black precipitates form, rendering the cells visible against an unstained background.
What is the result of the autocatalytic reaction in stained cells?
The majority of the cell can be visualized in its native tissue.
What are the specialized structures on postsynaptic target cells enriched with?
Neurotransmitter receptors.
Who first coined the phrase 'nature vs. nurture'?
Francis Galton in the 1800s.
How do neurons communicate via electrical synapses?
Through gap junctions.
What do gap junctions allow to travel between adjacent neurons?
Ions and small molecules.
What is the role of Wernicke's area?
It is associated with difficulty understanding language.
What does the neuron doctrine state?
Neuronal processes do not fuse together to form a continuous reticulum; neurons communicate at distinct contact sites called synapses.
What are basket cells known for?
They wrap their axon terminals around the cell bodies of pyramidal cells in the cerebral cortex and Purkinje cells in the cerebellum.
What characterizes a multipolar neuron?
It has both dendrites and an axon leaving the cell body.
What type of neuron are somatosensory neurons classified as?
Pseudounipolar neurons.
What is the function of microglia?
They act as immune cells, engulfing damaged cells and debris, and help reorganize neuronal connections.
What do oligodendrocytes and Schwann cells do?
They wrap axons with myelin sheaths in their respective parts of the nervous system.
What comprises spinal reflexes in vertebrates?
A sensory neuron that receives external stimuli and a motor neuron that controls muscle contraction.
What is synaptic transmission?
The process of neurotransmitter release from the presynaptic neuron and neurotransmitter reception at the postsynaptic neuron.
What is the correlation between identical twins and IQ?
0.86.
What did Mathias Schleiden and Theodor Schwann propose in 1839?
The cell theory: all living organisms are composed of cells as their basic units.
What is the function of Broca's area?
It is responsible for our ability to speak and have good understanding.
What is the most commonly encountered neuron in the mammalian cerebral cortex?
The pyramidal neuron.
Who coined the term 'synapses'?
Charles Sherrington.
What are the four subtypes of glial cells?
Oligodendrocytes, Schwann cells, Astrocytes, and Microglia.
What role do astrocytes play in the nervous system?
They are involved in neural development and regulation of neuronal communication.
What initiates the avoidance response in zebrafish larvae?
A sensory neuron detects a splash of water.
What is the role of the motor neuron in the zebrafish larvae's response?
It communicates impulses to run.
What is electron microscopy used for?
To visualize structures at nanometer resolution.
What are identical twins also known as?
Monozygotic twins.
How did barn owls adapt to the prisms in the experiment?
They adjusted their auditory map to match their visual map.
What is neuroethology?
The field of study that emphasizes observing animal behavior in their natural environments.
What do gain of function experiments involve?
Adding a specific component to the system.
What significant invention did Camillo Golgi create?
The Golgi stain.
What structure leads axons and changes shape dynamically?
Growth cone.
What are neurons considered according to Ramon y Cajal?
Functionally, structurally, and embryonically independent units of the nervous system.
What happens during the development of neurons?
Neurons start with only cell bodies, and axons grow out from the cell bodies to their final destinations.
What experimental technique allowed observation of axon growth?
In vitro experiments made possible by tissue culturing techniques.
Who proposed the theory of dynamic polarization?
Ramon y Cajal.
How do myelin sheaths affect information propagation?
They increase the speed at which information is propagated along axons.
What specialized apparatus do sensory neurons embed their endings in for the knee jerk reflex?
Muscle spindles.
How do sensory neurons detect the stretching of muscle spindles?
By converting the physical impact of the hammer into electrical signals (receptor potentials).
What are nerves?
Discrete bundles of axons.
What is the correlation between dizygotic twins and IQ?
0.60.
What are the two sides of the brain called?
Hemispheres.
What are epigenetic modifications?
Changes made to DNA and chromatin that alter gene expression without modifying DNA sequences.
What are dendritic spines?
Protrusions on dendrites that specialize in information transfer.
What is an action potential?
The elementary unit of nerve impulses propagated along axons.
What is a sensory homunculus?
A representation of the sensory areas of the body in the brain.
What is an example of a perturbation experiment?
Putting prisms on a barn owl.
What is the length of the synaptic cleft?
20-100 nm.
Where is the action potential initiated in sensory neurons?
At the junction between terminal endings and the peripheral axon.
How is information transmitted in sensory neurons?
By the peripheral and central axon to the spinal cord across a long distance.
Where does action potential initiation likely occur in invertebrate neurons?
At the junction between the dendritic and axonal compartments.
How is information transmitted at electrical synapses?
By a membrane potential change in ions across the gap junction.
What triggers neurotransmitter release at chemical synapses?
Arrival of action potentials at presynaptic terminals.
What is neuroplasticity?
Changes in the nervous system in response to experience and learning.
What is white matter composed of in the CNS?
Oligodendrocytes and myelinated axons.
What does interneuronal communication rely on?
Neurotransmitter release and reception at chemical synapses.
What does the spinal cord motor neuron project its axon into?
Muscle.
What are releasers in the context of fixed action patterns?
The essential features of the stimulus that activate the fixed action pattern.
What is convergent excitation?
When several neurons synapse onto a postsynaptic neuron.
How is the mammalian brain organized?
It consists of the cerebral cortex, basal ganglia, hippocampus, amygdala, thalamus, hypothalamus, cerebellum, and brainstem.
What was the purpose of putting prism glasses on barn owls in the experiment?
To distort their vision and study the correlation between auditory and visual systems.
What are dendrites?
Thick, bushy processes that receive information.
What type of neurons are usually found in invertebrates?
Unipolar neurons, which extend a single process giving rise to both dendritic and axonal branches.
What is the axon initial segment (axon hillock)?
The site of action potential initiation.
What does the theory of dynamic polarization state?
Transmission of neuronal signals proceeds from dendrites to cell bodies to axons.
What is gray matter composed of in the CNS?
Astrocytes, neuronal cell bodies, dendrites, axon terminals, and connections between neurons.
How is intraneuronal communication achieved?
By membrane potential changes in the form of graded potentials and action potentials.
What happens after sensory neurons propagate electrical signals to the spinal cord?
They release neurotransmitters onto the dendrites of motor neurons.
What are neural circuits?
Ensembles of interconnected neurons that work together to perform a specific function.
What are circuit motifs in the nervous system?
Common configurations of neural circuits that allow specific functions.
What are the main components of the central nervous system (CNS)?
The brain and spinal cord.
What are presynaptic terminals?
The ends of axons that specialize in the transmission of information between neurons.
What is the role of axons in a neuron?
Axons send information.
What are synaptic potentials?
A type of graded potential produced at postsynaptic sites in response to neurotransmitter release.
What type of neuron extends a single process that bifurcates in the somatosensory system?
Sensory neuron.
What are nonidentical twins also known as?
Dizygotic twins.
What is the function of the axons of motor neurons in the knee jerk reflex?
They extend outwards from the spinal cord and terminate in the same extensor muscle.
How does neuroplasticity change with age?
It declines with age; juvenile owls adapt more quickly than adult owls.
What does the neuraxis refer to?
The rostral-caudal axis or CNS axis.
What are the two major categories of cells in the CNS?
Neurons and glial cells.
What are typical neurons characterized by?
Having two neuronal processes (cytoplasmic extensions).
What are axons?
Long, thin processes that extend far beyond the cell body.
What is the function of dendrites in a neuron?
Dendrites receive information.
How do neurons convey the intensity of signals?
By using the frequencies of action potentials.
What are fixed action patterns?
Instinctive behaviors.
What are ganglia?
Clusters of cell bodies of nerve cells.
What is the heritability of IQ calculated from the twin studies?
0.52.
What are axonal branches also known as?
Collaterals.
What are the three developmental regions of the brain?
Forebrain, midbrain, and hindbrain.
What segments make up the spinal cord?
Cervical, thoracic, lumbar, and sacral groups.
What does the peripheral nervous system (PNS) include?
Nerves and ganglia.
What is the cell body of a neuron?
The center of the neuron.
What are graded potentials?
Membrane potentials that vary continuously in magnitude, induced by sensory stimuli.
What was the reticular theory regarding the nervous system?
It proposed that nerve cells were linked together to form a giant net, or reticulum, constituting the unit of the nervous system.
How is heritability defined?
The contribution of genetic differences to trait differences.
How is the nervous system traditionally examined?
In three sections: transverse, sagittal, and horizontal.
What is an example of instinctive behavior in animals?
A baby penguin nudging the beak of its parent for food.
What does 'innate' refer to in the context of behavior?
Something genetically programmed within an organism from birth.
What are the three main components of a neuron?
Who discovered that electric current could generate muscle twitches in frogs?
Luigi Galvani.