The first major renal process is ___ filtration.
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Glomerular
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The first major renal process is ___ filtration.
Glomerular
The second major renal process is ___ reabsorption.
Tubular
The third major renal process is ___ secretion.
Tubular
The renal corpuscle consists of the glomerular (Bowman's) capsule and the ___.
glomerulus
The glomerulus is made up of ___ capillaries.
fenestrated
Blood flows from the ___ arteriole through the glomerulus, which consists of ___ capillaries.
afferent, fenestrated
The glomerulus forms ___ from blood plasma while preventing ___ and ___ from passing.
filtrate, plasma proteins, blood cells
The parietal layer of the glomerular capsule is made up of ___ epithelium.
simple squamous
The visceral layer of the glomerular capsule consists of specialized epithelial cells called ___.
podocytes
Podocytes have ___ processes that surround glomerular capillaries.
foot
The filtration membrane in the kidney consists of the capillary endothelium, ___, and foot processes of podocytes.
basement membrane
The movement of blood plasma through ___ is a key feature of the filtration membrane.
fenestrations
The filtrate enters the ___ after passing through the filtration membrane.
capsular space
The filtration slits are formed by the ___ of podocytes.
foot processes
The fenestrated endothelium of the glomerular capillaries allows the passage of all plasma components, but does not allow the passage of ___ cells.
blood
The basement membrane and slit diaphragm restrict the passage of ___.
macromolecules
Macromolecules that are trapped in the basement membrane are engulfed by ___ cells.
glomerular mesangial
Blood enters the glomerular capillaries from the ___ arteriole.
afferent
Urea enters the ascending limb of the loop of Henle via ___ diffusion.
facilitated
Active transport of NaCl occurs in the ___ segment of the ascending limb.
thick
Urea enters the filtrate by ___ diffusion.
facilitated
In the descending limb of the Loop of Henle, it is impermeable to ___ but permeable to ___.
NaCl, water
The concentration of filtrate ___ in the descending limb because water is moving out and reentering the blood.
increases
In the ascending limb of the Loop of Henle, it is impermeable to ___ but permeable to ___.
water, NaCl
The concentration of filtrate ___ in the ascending limb because NaCl is moving out and reentering the blood.
decreases
In the distal convoluted tubule, Na+ reabsorption and K+ secretion are regulated by ___.
aldosterone
Cl- is cotransported with Na+ in the distal convoluted tubule through ___.
facilitated diffusion
Ca2+ reabsorption in the distal convoluted tubule is regulated by ___.
parathyroid hormone (PTH)
Water reabsorption in the distal convoluted tubule is regulated by ___.
antidiuretic hormone (ADH)
Water reabsorption in the collecting duct is regulated by ___.
ADH (antidiuretic hormone)
Na+ reabsorption and K+ secretion in the collecting duct are regulated by ___.
aldosterone
The collecting duct plays a role in maintaining blood pH by reabsorbing or secreting ___.
H+ and HCO3-
___ is secreted in the collecting duct to help maintain blood pH.
NH4+
Urea is reabsorbed in the collecting duct through ___.
passive transport
Urea moves out of the collecting duct through ___ diffusion.
facilitated
One function of the urinary system is ___.
Excretion
The urinary system helps in the regulation of ___ levels in the body fluids.
body fluid
The urinary system plays a role in regulating the ___ of body fluid.
pH
The urinary system regulates the ___ in body fluid.
solutes
The urinary system secretes ___.
renin
The urinary system is responsible for secreting ___.
erythropoietin
The urinary system is involved in the metabolism of ___.
Vitamin D
The urinary system can perform ___ during periods of fasting.
gluconeogenesis
The kidneys are located on the posterior abdominal wall lateral to ___ - ___ vertebrae.
T12, L3
The ureters are located on the posterior abdominal wall lateral to the ___ vertebrae, and within the ___ cavity.
lumbar, pelvic
The urinary bladder is located within the pelvic cavity, directly posterior to the ___ bones.
pubic
In females, the urethra is located within the perineum; anterior to the ___; in males, it is located anterior to the anal canal and within the ___.
vagina, penis
The kidneys are located in the ___ space.
retroperitoneal
The ___ helps anchor the kidneys to other structures.
renal fascia
The ___ protects the kidney from physical damage.
perirenal fat capsule
The ___ is a transparent layer that prevents infection from spreading to the kidney.
fibrous capsule
Total body water varies by ___, ___, muscle mass and body fat percentage.
age, sex
Skeletal muscle contains ___% water, while adipose tissue contains ___% water.
75, 20
Total body water decreases with ___.
age
The lungs exchange ___ which goes from the lungs to the blood, and ___ which goes from the blood to the lungs.
Oxygen (O2), Carbon Dioxide (CO2)
The digestive tract provides ___, ___, and ___ into the blood.
Nutrients, Water (H2O), Ions
The kidneys and liver both send ___ into the blood.
Wastes
Oxygen (O2), Carbon Dioxide (CO2), Nutrients, Water (H2O) and Ions, and Wastes are transported into the ___ from the blood plasma.
interstitial fluid
The final transport of substances occurs from the interstitial fluid into the ___ in tissue cells.
intracellular fluid
The average daily water intake from beverages is ___ ml, making up ___% of the total.
1500, 60
The average daily water intake from foods is ___ ml, accounting for ___% of the total.
750, 30
The average daily water intake from metabolism is ___ ml, which is ___% of the total.
250, 10
The average daily water output through urine is ___ ml, representing ___% of the total.
1500, 60
The average daily water output through losses via skin and lungs is ___ ml, making up ___% of the total.
700, 28
The average daily water output through sweat is ___ ml, which accounts for ___% of the total.
200, 8
The average daily water output through feces is ___ ml, representing ___% of the total.
100, 4
Electrolytes are chemical compounds that ___ into ions in water.
dissociate
Nonelectrolytes are chemical compounds that do not ___ in water.
dissociate
In the ECF, the cation concentration of Na+ is ___ mEq/l.
200
In the ICF, the anion concentration of HCO3- is ___ mEq/l.
150
The concentration of K+ in the ECF is ___ mEq/l.
100
The concentration of Cl- in the ICF is ___ mEq/l.
50
The kidneys are the major ___ organ of the body.
excretory
Each kidney contains over ___ million nephrons.
one
___% of the filtrate is reabsorbed into the blood.
99
Only ___% of the filtrate becomes urine.
1
Each nephron consists of a renal corpuscle and a ___ convoluted tubule.
proximal
The renal corpuscle includes the glomerulus and ___ capsule.
glomerular (Bowman’s)
The loop of Henle has a ___ limb and an ascending limb.
descending
The nephron's collecting duct connects to the ___ convoluted tubule.
distal
The functional unit of the kidney is the ___.
nephron
The pathway of blood flow from the ___ artery to the ___ vein includes the glomerulus and peritubular capillaries.
arcuate, arcuate
Blood flows from the arcuate artery to the ___ arteriole before reaching the glomerulus.
afferent
After passing through the glomerulus, blood exits via the ___ arteriole.
efferent
The blood from the peritubular capillaries returns to the arcuate vein through the ___ vein.
cortical radiate
Urine production in the kidneys results from ___ major renal processes.
3
Blood is filtered through the endothelium of the capillaries, basement membrane, and ___ to become filtrate in the glomerular capsule.
podocytes
Blood that is not filtered into the glomerular capsule will pass into the ___ arteriole.
efferent
The efferent arteriole leads to either ___ (juxtaglomerular nephron) or ___ (cortical nephron).
vasa recta, peritubular capillaries
Most plasma proteins ___ pass into the filtrate.
do not
About ___% of albumins is excreted in the urine.
1
Proteinuria results from defects in ___ or ___ that lead to more excretion of plasma proteins in the urine.
filtration, reabsorption
Proteinuria can lead to ___, ___, and hydrothorax.
edema, ascites
The ___ capillaries receive reabsorbed substances from the proximal and distal convoluted tubules.
Peritubular
The Juxtamedullary nephron has a ___ loop of Henle.
long
In the Juxtamedullary nephron, the glomerulus is located closer to the ___ junction.
corticomedullary
The efferent arteriole of the Juxtamedullary nephron supplies the ___.
vasa recta
The Cortical nephron has a ___ loop of Henle.
short
In the Cortical nephron, the glomerulus is located further from the ___ junction.
corticomedullary
The efferent arteriole of the Cortical nephron supplies the ___ capillaries.
peritubular
The ___ receive reabsorbed substances from the loop of Henle.
Vasa recta
In the proximal convoluted tubule, ___% of glucose, lactate, and amino acids in filtrate are reabsorbed.
100
The proximal convoluted tubule reabsorbs ___% of sodium and water.
65
___% of bicarbonate ions are reabsorbed in the proximal convoluted tubule.
80
The proximal convoluted tubule reabsorbs ___% of chloride ions.
60
___% of potassium ions are reabsorbed in the proximal convoluted tubule.
55
In the proximal convoluted tubule, ___% of urea is reabsorbed.
50
In the proximal convoluted tubule, ___, glucose, amino acids, and other nutrients are actively transported.
Na+
Water, urea, and many ions follow passively after ___ transport in the proximal convoluted tubule.
active
___ and ammonium ion (NH4+) are secreted in the proximal convoluted tubule.
H+
___ is reabsorbed in the proximal convoluted tubule.
HCO3-
Some ___ are secreted in the proximal convoluted tubule.
drugs
The descending limb of the loop of Henle is freely permeable to ___.
water
The epithelium of the descending limb of the loop of Henle is composed of ___ epithelium.
simple squamous
The ascending limb of the loop of Henle is ___ to water.
impermeable
The thick segment of the ascending limb has ___ epithelium.
simple cuboidal
In the thin segment of the ascending limb, NaCl and K+ are reabsorbed by ___ diffusion.
facilitated
The concentration of urea in the descending limb of the nephron loop increases from ___ to ___ as it progresses down the loop.
300, 1200
The ascending limb of the loop of Henle has a urea concentration of ___.
100
The flow of filtrate begins at the ___.
Glomerulus
After the glomerulus, filtrate moves to the ___ convoluted tubule.
Proximal
The ___ of Henle consists of a descending limb and an ascending limb.
Loop
Filtrate then passes into the ___ convoluted tubule.
Distal
The final stage of filtrate flow is through the ___ ducts before emptying into a minor calyx.
Papillary
Each kidney contains approximately ___ million nephrons.
1.3
The renal cortex contains ___ .
(specific structures or functions to be filled in)
The renal pyramids in the medulla contain ___ .
(specific structures or functions to be filled in)
Minor calyces are responsible for ___ .
(specific functions to be filled in)
Major calyces are responsible for ___ .
(specific functions to be filled in)
The renal pelvis is the ___ .
(specific functions to be filled in)
The ___ connects the kidney to the urinary bladder.
Ureter
The structure that collects urine from the kidney is called the ___ .
Renal pelvis
The ___ is the structure that stores urine before it is excreted.
Urinary bladder
The urinary bladder is a ___ sac that can distend to store up to ~1 L of urine.
muscular
The innermost layer of the urinary bladder wall is called the ___ epithelium.
Transitional
The thickest layer of the urinary bladder wall is the ___ muscle layer.
Smooth
The layer beneath the epithelium in the urinary bladder wall is known as the ___ tissue (lamina propria).
Connective
The urethra carries urine from the urinary bladder to the ___ environment.
external
The male urethra extends from the bladder through the ___ and down the penis.
prostate
The part of the male urethra that is surrounded by the external urethral sphincter is called the ___ part.
intermediate (membranous)
The ___ is the structure that connects the bladder to the urethra in males.
prostate
The external urethral orifice is located at the end of the ___ urethra.
spongy